To analyze the effect of connexin loss on the repair of wounded tail skin, we have studied
the following transgenic mouse mutants: connexin30–/–, connexin31–/–and connexin43 Cre …

We show that connexin expression and in vivo patterns of communication were dramatically
altered in response to epidermal wounding. Six hours after injury, Cx26 was up-regulated in …

Wound healing is a complex process requiring communication for the precise co‐ordination
of different cell types. The role of extracellular communication through growth factors in the …

Gap junctions (GJ) are known to be involved in spontaneous wound healing in rodent skin.
We analyzed the staining patterns of the GJ proteins Cx26, Cx30, and Cx43 in human …

Background Regulated alteration of connexin expression has been shown to be integral to
acute wound repair. Downregulation of the gap‐junction protein connexin 43 at the wound …

Eight different connexins are expressed in mouse epidermis with overlapping expression
patterns in different epidermal layers. Analyses of mice with deficiency or modifications of …

We examined changes in the expression and localization of connexin proteins and
transcripts by means of immunofluorescence and in situ hybridization in normal conditions …

Nonhealing cutaneous wounds, a major cause of morbidity and mortality, are difficult to treat.
Recent studies suggest that significant increases in skin wound‐healing rates occur by …

In the present review, we provide an overview of connexin expression during skin
development and remodeling in wound healing, and reflect on how loss-or gain-of-function …

In the epidermis, remodelling of Connexin43 is a key event in wound closure. However,
controversy between the role of connexin channel and non-channel functions exist. We …