Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34–q35. 2

I Reynisdottir, G Thorleifsson, R Benediktsson… - The American Journal of …, 2003 - cell.com
We report a genomewide linkage study of type 2 diabetes (T2D [MIM 125853]) in the
Icelandic population. A list of type 2 diabetics was cross-matched with a computerized …

Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility locus in northern European Caucasians

SK Das, SJ Hasstedt, Z Zhang, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc
We have identified a region on chromosome 1q21-q24 that was significantly linked to type 2
diabetes in multiplex families of Northern European ancestry and also in Pima Indians …

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

R Duggirala, J Blangero, L Almasy, TD Dyer… - The American Journal of …, 1999 - cell.com
Since little is known about chromosomal locations harboring type 2 diabetes–susceptibility
genes, we conducted a genomewide scan for such genes in a Mexican American …

The search for type 2 diabetes susceptibility loci: the chromosome 1q story

SK Das, SC Elbein - Current diabetes reports, 2007 - Springer
The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of
type 2 diabetes mellitus to the chromosome 1q21–25 region in at least eight independent …

A genomewide scan for loci predisposing to type 2 diabetes in a UK population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides …

S Wiltshire, AT Hattersley, GA Hitman, M Walker… - The American Journal of …, 2001 - cell.com
Improved molecular understanding of the pathogenesis of type 2 diabetes is essential if
current therapeutic and preventative options are to be extended. To identify diabetes …

Genomewide search for type 2 diabetes–susceptibility genes in French Whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27 …

N Vionnet, S Dupont, S Gallina, S Francke… - The American Journal of …, 2000 - cell.com
Despite recent advances in the molecular genetics of type 2 diabetes, the majority of
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …

Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13. 1-q13. 2.

T Klupa, MT Malecki, M Pezzolesi, L Ji, S Curtis… - Diabetes, 2000 - Am Diabetes Assoc
We previously reported suggestive linkage between type 2 diabetes and markers in a region
on chromosome 20q using data from a collection of 29 Caucasian families in which type 2 …

A genome-wide scan in type 2 diabetes mellitus provides independent replication of a susceptibility locus on 18p11 and suggests the existence of novel Loci on 2q12 …

JHO Van Tilburg, LA Sandkuijl… - The Journal of …, 2003 - academic.oup.com
A genome-wide scan was performed, using nonparametric linkage analyses, to find
susceptibility loci for type 2 diabetes mellitus in the Dutch population. We studied 178 …

Evidence for a Type 1 Diabetes Susceptibility Locus (IDDM10) on Human Chromosome 10p11–q11

P Reed, F Cucca, S Jenkins, M Merriman… - Human molecular …, 1997 - academic.oup.com
A region of linkage to type 1 diabetes has been defined on human chromosome 10p11–q11
(IDDM10; P= 0.0007) using 236 UK and 76 US affected sibpairs and a 1 cM resolution …

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11

A Parker, J Meyer, S Lewitzky, JS Rennich, G Chan… - Diabetes, 2001 - Am Diabetes Assoc
Genome-wide nonparametric linkage analysis of 480 sib-pairs affected with type 2 diabetes
revealed linkage to a previously unreported susceptibility locus on chromosome 18p11. This …