Background Myocardial regeneration via stem-cell mobilisation at the time of myocardial
infarction is known to occur, although the mechanism for stem-cell homing to infarcted tissue …

A concentration gradient of stromal-cell-derived factor-1α (SDF-1α) is the major mechanism
for homing of haematopoietic stem cells (HSCs) in bone marrow. We tested the hypothesis …

We aimed to optimize non-viral transfection of human stromal cell derived factor (SDF-1α)
gene into skeletal myoblasts (SkM) and, transplant these cells to establish transient SDF-1α …

Background—After myocardial infarction (MI), bone marrow–derived cells (BMDCs) are
found within the myocardium. The mechanisms determining BMDC recruitment to the heart …

Objective The chemokine stromal cell–derived factor–1 (SDF–1) has been implicated in
homing of bone marrow cells to sites of injury. We investigated the time course of myocardial …

Background—Local delivery of chemotactic factors represents a novel approach to tissue
regeneration. However, successful chemokine protein delivery is challenged by barriers …

Prolongation or reestablishment of stem cell homing through the expression of SDF-1 in the
myocardium has been shown to lead to homing of endothelial progenitor cells to the infarct …

Background—Stromal cell-derived factor-1 (SDF-1) is a chemoattractant of stem/progenitor
cells, and several studies have shown that SDF-1 may improve ventricular function after …

Stem cell transplantation at the time of acute myocardial infarction (AMI) improves cardiac
function. Whether the improved cardiac function results from regeneration of cardiac …

Aims Previous experimental studies have suggested that platelet stromal-cell-derived factor-
1 (SDF-1) regulates mobilization and recruitment of haematopoietic progenitor cells …