CXCL12 expression by invasive trophoblasts induces the specific migration of CD16– human natural killer cells
In the maternal decidua, natural killer (NK) cells, characterized by lack of CD16, are found in
direct contact with the fetal extravillous trophoblasts (EVTs). It is yet unknown which factors …
direct contact with the fetal extravillous trophoblasts (EVTs). It is yet unknown which factors …
Human trophoblasts recruited T lymphocytes and monocytes into decidua by secretion of chemokine CXCL16 and interaction with CXCR6 in the first-trimester …
Y Huang, XY Zhu, MR Du, DJ Li - The Journal of Immunology, 2008 - journals.aai.org
During human early pregnancy, fetus-derived trophoblasts come into direct contact with
maternal immune cells at the maternofetal interface. At sites of placental attachment …
maternal immune cells at the maternofetal interface. At sites of placental attachment …
Human first-trimester trophoblast cells recruit CD56brightCD16− NK cells into decidua by way of expressing and secreting of CXCL12/stromal cell-derived factor 1
X Wu, LP Jin, MM Yuan, Y Zhu, MY Wang… - The Journal of …, 2005 - journals.aai.org
More than 70% of decidual lymphocytes are NK cells characterized by CD56 bright CD16−
phenotype, but the mechanisms by which these NK cells are recruited in the decidua are still …
phenotype, but the mechanisms by which these NK cells are recruited in the decidua are still …
Trophoblast-derived CXCL16 induces M2 macrophage polarization that in turn inactivates NK cells at the maternal–fetal interface
XQ Wang, WJ Zhou, XX Hou, Q Fu, DJ Li - Cellular & Molecular …, 2018 - nature.com
Decidual macrophages (dMΦ) are distinct from the conventional macrophages present in
other tissues and express M2 macrophage markers, but the molecular mechanisms of …
other tissues and express M2 macrophage markers, but the molecular mechanisms of …
Chemokine CXCL16, a scavenger receptor, induces proliferation and invasion of first-trimester human trophoblast cells in an autocrine manner
Y Huang, XY Zhu, MR Du, X Wu, MY Wang… - Human …, 2006 - academic.oup.com
BACKGROUND: The aim of this study was to investigate whether CXCL16/CXCR6, a newly
identified chemokine pair, is expressed in first-trimester human placenta and whether they …
identified chemokine pair, is expressed in first-trimester human placenta and whether they …
Trophoblast-derived chemokine CXCL12 promotes CXCR4 expression and invasion of human first-trimester decidual stromal cells
L Ren, YQ Liu, WH Zhou, YZ Zhang - Human reproduction, 2012 - academic.oup.com
BACKGROUND The aim of this study was to investigate the role of the chemokine (CXC
motif) ligand 12/chemokine (CXC motif) receptor 4 (CXCL12/CXCR4) axis on the crosstalk …
motif) ligand 12/chemokine (CXC motif) receptor 4 (CXCL12/CXCR4) axis on the crosstalk …
The expression and possible roles of chemokine CXCL11 and its receptor CXCR3 in the human endometrium
IFN-γ secreted by a human embryo and trophoblast cells during implantation is suggested to
play an important role in implantation and pregnancy. In the present study, we explored …
play an important role in implantation and pregnancy. In the present study, we explored …
Chemokine CXCL12 promotes the cross-talk between trophoblasts and decidual stromal cells in human first-trimester pregnancy
WH Zhou, MR Du, L Dong, J Yu, DJ Li - Human reproduction, 2008 - academic.oup.com
BACKGROUND The precise mechanisms in the materno-fetal dialogue still remain unclear.
The aim of this study was to investigate the role of the chemokine CXCL12 and its receptor …
The aim of this study was to investigate the role of the chemokine CXCL12 and its receptor …
CXCL10 and IL-6 induce chemotaxis in human trophoblast cell lines
F Dominguez, S Martinez, A Quinonero… - Molecular human …, 2008 - academic.oup.com
The investigation of trophoblast chemoattractive molecules in humans is of high interest for
the reproductive field. Current evidence in ruminants demonstrates that CXCL10, formerly …
the reproductive field. Current evidence in ruminants demonstrates that CXCL10, formerly …
CX3CL1 and CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast: potential roles in human embryo implantation
NJ Hannan, LA Salamonsen - Biology of reproduction, 2008 - academic.oup.com
Embryo implantation is a complex process involving blastocyst attachment to the
endometrial epithelium and subsequent trophoblast invasion of the decidua. We have …
endometrial epithelium and subsequent trophoblast invasion of the decidua. We have …