A novel function of connexin 32: marked enhancement of liver function in a hepatoma cell line

J Yang, A Ichikawa, T Tsuchiya - Biochemical and Biophysical Research …, 2003 - Elsevier
Connexin 32 (Cx32) is the main gap junction protein in hepatocytes and plays an important
role in the regulation of signal transfer and growth control in the liver by constructing gap …

Induction and regulation of connexin26 by glucagon in primary cultures of adult rat hepatocytes

T Kojima, T Mitaka, Y Shibata… - Journal of cell …, 1995 - journals.biologists.com
In the adult rat hepatocyte, the gap junction proteins consist of a major component,
connexin32 (Cx32) and a minor component, connexin26 (Cx26). Although we recently …

Liver cell-specific transcriptional regulation of connexin32

MP Piechocki, RM Toti, MJ Fernstrom, RD Burk… - … et Biophysica Acta (BBA …, 2000 - Elsevier
Gap junctional intercellular communication facilitates liver homeostasis and growth control
in the liver. The major gap junction protein expressed by hepatocytes is connexin32 (Cx32) …

Expression of gap junction protein connexin32 in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma

Y Nakashima, T Ono, A Yamanoi, ON El-Assal… - Journal of …, 2004 - Springer
Background The gap junction (GJ) plays important roles in the maintenance of tissue
homeostasis, the control of cell growth and differentiation, and the prevention of …

Reduction of malignant phenotype of HEPG2 cell is associated with the expression of connexin 26 but not connexin 32

T Yano, FJ Hernandez-Blazquez, Y Omori… - …, 2001 - academic.oup.com
Connexin (Cx) genes have a negative growth effect on tumour cells with certain specificity.
However, it is not clear whether each Cx gene can act similarly in growth control …

[HTML][HTML] Expression of gap junction genes connexin 32, connexin 43 and their proteins in hepatocellular carcinoma and normal liver tissues

XD Ma, YF Sui, WL Wang - World Journal of Gastroenterology, 2000 - ncbi.nlm.nih.gov
AIM: To investigate the significance and mechanism of cx-32 mRNA, cx-43 mRNA and their
proteins in hepatocarcinogenesis. METHODS: Sixty-one cases of HCC and 14 cases of …

[HTML][HTML] Expression of gap junction genes connexin 32 and connexin 43 mRNAs and proteins, and their role in hepatocarcinogenesis

XD Ma, X Ma, YF Sui, WL Wang - World Journal of …, 2002 - ncbi.nlm.nih.gov
AIM: To investigate the relationship between hepatocarcinogenesis and the expression of
connexin32 (cx32), connexin43 (cx43) mRNAs and proteins in vitro. METHODS: Gap …

Reappearance and long-term maintenance of connexin32 in proliferated adult rat hepatocytes: use of serum-free L-15 medium supplemented with EGF and DMSO

T Kojima, T Mitaka, DL Paul, M Mori… - Journal of Cell …, 1995 - journals.biologists.com
Intercellular communication, especially gap junctional communication, is thought to be one
of the highly differentiated functions of hepatocytes. In primary cultures of rat hepatocytes, it …

Cytoplasmic accumulation of connexin32 protein enhances motility and metastatic ability of human hepatoma cells in vitro and in vivo

Q Li, Y Omori, Y Nishikawa, T Yoshioka… - … journal of cancer, 2007 - Wiley Online Library
Connexins have long been believed to suppress tumour development during
carcinogenesis by exerting gap junctional intercellular communication (GJIC). Although …

Development of gap junctional channels and intercellular communication in rat liver during ontogenesis

M Iwai, Y Harada, A Muramatsu, S Tanaka, T Mori… - Journal of …, 2000 - Elsevier
Background/Aims: We investigated the expression of connexin (Cx) 32 and 26 subunit
proteins of the gap junction (GJ) in the rat liver during ontogenesis to clarify their roles in …