Oligosaccharides transact information exchange at the cell surface and modulate the
activities and distribution of proteins within cells. Recently, the ability to modify …

Many adhesion and signaling molecules critical for development, as well as surface markers
implicated in diseases ranging from cancer to influenza, contain oligosaccharides that …

Glycans form one of the four classes of biomolecules, are found in every living system and
present a huge structural and functional diversity. As an illustration of this diversity, it has …

The contributions of cell surface oligosaccharides to critical biological processes such as
leukocyte—endothelial cell adhesion, bacterial and viral infection, and immunological …

▪ Abstract Oligosaccharides play a crucial role in many of the recognition, signaling, and
adhesion events that take place at the surface of cells. Abnormalities in the synthesis or …

Glycosylation is how proteins and lipids are modified with complex carbohydrates known as
glycans. The post-translational modification of proteins with glycans is not a template-driven …

Glycans are involved in numerous biological recognition events. Being secondary gene
products, their labeling by genetic methods–comparable to GFP labeling of proteins–is not …

Cellular carbohydrates or glycans are critical mediators of biological function. Their
remarkably diverse structures and varied activities present exciting opportunities for …

The structural diversity of glycans on cells—the glycome—is vast and complex to decipher.
Glycan arrays display oligosaccharides and are used to report glycan hapten binding …

The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …