[图书][B] Immunochemical methods for biomonitoring of chlorophenols as potential biomarkers of exposure

MI Nichkova - 2003 - diposit.ub.edu
[eng] The thesis presents the development of immunochemical methods for detection of
trichlorophenols (TCP) in environmental and biological samples. An indirect enzyme linked …

Competitive quenching fluorescence immunoassay for chlorophenols based on laser-induced fluorescence detection in microdroplets

M Nichkova, J Feng, F Sanchez-Baeza… - Analytical …, 2003 - ACS Publications
An improved biomonitoring system for the analysis of 2, 4, 6-trichlorophenol (TCP) in urine
samples has been developed. The principle of the biosensor device is the detection of laser …

Development and evaluation of C18 and immunosorbent solid-phase extraction methods prior immunochemical analysis of chlorophenols in human urine

M Nichkova, MP Marco - Analytica chimica acta, 2005 - Elsevier
Two solid-phase extraction (SPE) methods, based on hydrophobic and selective (antibody–
antigen) interactions, have been established and evaluated as clean-up methods prior the …

Biological monitoring of 2, 4, 5-trichlorophenol (II): evaluation of an enzyme-linked immunosorbent assay for the analysis of water, urine, and serum samples

M Nichkova, R Galve, MP Marco - Chemical research in toxicology, 2002 - ACS Publications
Chlorophenols are frequently found in the urine of the population as consequence of the
widespread use of chlorophenols and other organochlorinated compounds. An …

Biomonitoring human exposure to organohalogenated substances by measuring urinary chlorophenols using a high-throughput screening (HTS) immunochemical …

M Nichkova, MP Marco - Environmental science & technology, 2006 - ACS Publications
The widespread contamination of the environment by persistent organochlorinated
substances is well-known. High-throughput immunochemical methods may improve routine …

Development of an enzyme-linked immunosorbent assay for screening contamination by chlorophenols in environmental waters

P Noguera, A Maquieira, R Puchades… - Journal of …, 2002 - pubs.rsc.org
The development of an immunoassay for screening contamination by chlorophenols is
presented. Two haptens were synthesized and conjugated to immunizing proteins to raise …

Development and evaluation of an immunoassay for biological monitoring chlorophenols in urine as potential indicators of occupational exposure

R Galve, M Nichkova, F Camps… - Analytical …, 2002 - ACS Publications
Trichlorophenols (TCP) eliminated by the urine can be considered as potential biomarkers
of exposure of many chemicals (chlorophenols, chlorophenoxy acid herbicides, prochloraz …

Development of an enzyme-linked immunosorbent assay for the detection of pentachlorophenol residues in water samples

T Xu, H Jing, Q Li, S Liu, W Sheng… - Food and agricultural …, 2007 - Taylor & Francis
An indirect competitive enzyme-linked immunosorbent assay (ELISA) for pentachlorophenol
(PCP) was developed with a polyclonal antiserum produced against a hapten, 4-(2, 3, 5, 6 …

Development of an enzyme-linked immunosorbent assay for pentachlorophenol

P Noguera, Á Maquieira, R Puchades, E Brunet… - Analytica Chimica …, 2002 - Elsevier
Pentachlorophenol (PCP) is a hazardous pollutant with toxicity and potential carcinogenic
properties being a serious threat to the environment. In this work, the development of an …

A High-Throughput Screening Immunochemical Protocol for Biological Exposure Assessment of Chlorophenols in Urine Samples

M Nichkova, MP Marco - Pesticide Protocols, 2006 - Springer
This chapter presents a high-throughput screening (HTS) immunochemical procedure
suitable for processing and analyzing simultaneously multiple urine samples. The method …