Environmental pathogenic fungi present a paradox in that they are virulent in animals
without requiring animal hosts for replication or survival, a phenomenon we call 'ready …

The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …

Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Cryptococcus neoformans is the major causative agent of fungal meningoencephalitis in
both immunocompromised and immunocompetent individuals. During infection, this fungus …

Cryptococcus neoformans has become a common central nervous system pathogen as the
immunocompromised populations enlarge world-wide. This encapsulated yeast has …

The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

Why are some fungi pathogenic while the majority poses no threat to humans or other
hosts? Of the more than 1.5 million fungal species only about 150–300 are pathogenic for …

The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

ABSTRACT A library of more than 4,500 signature-tagged insertion mutants of the human
pathogenic fungus Cryptococcus neoformans was generated, and a subset was screened in …

Background Cryptococcus neoformans is an encapsulated yeast that is a facultative
intracellular pathogen. The interaction between macrophages and C. neoformans is critical …