Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis

HV Lin, A Rogulja, KM Cadigan - 2004 - journals.biologists.com
The Drosophila compound eye is formed by selective recruitment of undifferentiated cells
into clusters called ommatidia during late larval and early pupal development. Ommatidia at …

Acetylcholinesterase (AChE)-amyloid-β-peptide complexes in Alzheimer's disease. The Wnt signaling pathway

NC Inestrosa, S Urra… - Current Alzheimer …, 2004 - ingentaconnect.com
Alzheimer's disease (AD) is characterized by selective neuronal cell death, which is
probably caused by amyloid b-peptide (Aβ) oligomers and fibrils. We have found that …

Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development

SJ Ang, RJW Stump, FJ Lovicu, JW McAvoy - Gene Expression Patterns, 2004 - Elsevier
Recent studies indicate a role for Wnt signalling in regulating lens cell differentiation (Stump
et al., 2003). To further our understanding of this, we investigated the expression patterns of …

Secreted frizzled-related protein 2 (SFRP2) is highly expressed in canine mammary gland tumors but not in normal mammary glands

JL Lee, CJ Chang, SY Wu, DR Sargan… - Breast cancer research and …, 2004 - Springer
Canine mammary gland tumor (MGT) is the commonest tumor in female dogs and a good
animal model of human breast cancer. A group of newly identified genes encoding secreted …

Long‐term in vitro analysis of limb cartilage development: Involvement of Wnt signaling

KM Daumer, AC Tufan, RS Tuan - Journal of cellular …, 2004 - Wiley Online Library
Endochondral skeletal development involves the condensation of mesenchymal cells, their
differentiation into chondrocytes, followed by chondrocyte maturation, hypertrophy, and …

Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis

PL Coletta, AM Müller, EA Jones, B Mühl, S Holwell… - Blood, 2004 - ashpublications.org
Germ line mutations in the Adenomatous polyposis coli tumor suppressor gene cause a
hereditary form of intestinal tumorigenesis in both mice and man. Here we show that in Apc …

Wnt-frizzled signaling to G-protein-coupled effectors

HY Wang, CC Malbon - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
Wnt proteins signal via cell surface receptors termed Frizzleds. Frizzleds display many
properties characteristic of members of the superfamily of G-protein-coupled receptors …

Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless

C Chen, W Strapps, A Tomlinson… - Proceedings of the …, 2004 - National Acad Sciences
Members of the Frizzled family of serpentine transmembrane receptors are required to
transduce Wingless/Int (Wnt) signals and contain in their N-terminal regions a conserved …

PDE6 is an effector for the Wnt/Ca2+/cGMP-signalling pathway in development

H Wang, Y Lee, CC Malbon - Biochemical Society Transactions, 2004 - portlandpress.com
Wnt signalling in development operates via members of the Frizzleds, G-protein-coupled
receptors that bind specific Wnt ligands and mediate signalling via distinct pathways. The …

[PDF][PDF] Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development

Y Chen, RJW Stump, FJ Lovicu… - The International journal …, 2004 - researchgate.net
Recent studies indicate a role for Wnt signaling in regulating lens cell differentiation (Stump
et al., 2003). Here we investigated expression patterns of Wnt receptors, the Frizzleds (Fzs) …