Exercise training increases intramyocellular lipid and oxidative capacity in older adults

R Pruchnic, A Katsiaras, J He… - American Journal …, 2004 - journals.physiology.org
Intramyocellular lipid (IMCL) has been associated with insulin resistance. However, an
association between IMCL and insulin resistance might be modulated by oxidative capacity …

The increase in intramyocellular lipid content is a very early response to training

VB Schrauwen-Hinderling, P Schrauwen… - The Journal of …, 2003 - academic.oup.com
The present study investigated the influences of a 2-wk training program on intramyocellular
lipid (IMCL) content, IMCL decrease during exercise, fat oxidation, and insulin sensitivity …

Relative contribution of intramyocellular lipid to whole-body fat oxidation is reduced with age but subsarcolemmal lipid accumulation and insulin resistance are only …

C Chee, CE Shannon, A Burns, AL Selby… - Diabetes, 2016 - Am Diabetes Assoc
Insulin resistance is closely related to intramyocellular lipid (IMCL) accumulation, and both
are associated with increasing age. It remains to be determined to what extent perturbations …

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

JJ Dubé, F Amati, M Stefanovic-Racic… - American Journal …, 2008 - journals.physiology.org
We previously reported an “athlete's paradox” in which endurance-trained athletes, who
possess a high oxidative capacity and enhanced insulin sensitivity, also have higher …

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

BH Goodpaster, J He, S Watkins… - The Journal of Clinical …, 2001 - academic.oup.com
We examined the hypothesis that an excess accumulation of intramuscular lipid (IMCL) is
associated with insulin resistance and that this may be mediated by the oxidative capacity of …

Intramyocellular lipid content and insulin sensitivity are increased following a short-term low-glycemic index diet and exercise intervention

JM Haus, TPJ Solomon, L Lu… - American Journal …, 2011 - journals.physiology.org
The relationship between intramyocellular (IMCL) and extramyocellular lipid (EMCL)
accumulation and skeletal muscle insulin resistance is complex and dynamic. We examined …

Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation

G Perseghin, P Scifo, M Danna… - American Journal …, 2002 - journals.physiology.org
Intramyocellular lipid (IMCL) storage is considered a local marker of whole body insulin
resistance; because increments of body weight are supposed to impair insulin sensitivity …

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

LJC Van Loon, R Koopman… - American Journal …, 2004 - journals.physiology.org
Recent evidence suggests that intramyocellular lipid (IMCL) accretion is associated with
obesity and the development of insulin resistance and/or type 2 diabetes. However, trained …

[HTML][HTML] Accumulation of saturated intramyocellular lipid is associated with insulin resistance [S]

DB Savage, L Watson, K Carr, C Adams, S Brage… - Journal of lipid …, 2019 - ASBMB
Intramyocellular lipid (IMCL) accumulation has been linked to both insulin-resistant and
insulin-sensitive (athletes) states. Biochemical analysis of intramuscular triglyceride …

Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

C Thamer, J Machann, O Bachmann… - The Journal of …, 2003 - academic.oup.com
The existence of metabolically relevant intramyocellular lipids (IMCL) as assessed by the
noninvasive 1H-magnetic resonance spectroscopy (MRS) has been established. In the …