Newcomers to the field of biopharmaceuticals require an understanding of the basic
principles and underlying methodology involved in developing protein-and nucleic acid …

Over the past 60 years of development, biomaterials have demonstrated outstanding
versatility to ensure controlled, reproducible drug delivery. These drug delivery systems …

Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell
more easily, has advanced considerably in recent decades. Innovative medication delivery …

Publisher Summary This chapter elaborates the structure, function, and mechanism of
various polymeric vectors and their applicability in gene delivery. Polymers play a vital role …

Due to their low bioavailability, many naturally occurring proteins can not be used in their
native form in diseases caused by insufficient amounts or inactive variants of those proteins …

Advances in biotechnology have led to an accelerated discovery of macromolecular
therapeutics such as peptides, proteins and polynucleotides. These macromolecules can be …

Introduction: The delivery of nucleic acid therapeutics through non-viral carriers face multiple
biological barriers that reduce their therapeutic efficiency. Despite great progress, there …

Biomacromolecules have long been at the leading edge of academic and pharmaceutical
drug development and clinical translation. With the clinical advances of new therapeutics …

Effective delivery of nucleic acids requires overcoming cellular barriers that would otherwise
hinder transport of payload from the extracellular space to the cytoplasm or nucleus of a …

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene
therapy, a topic that has attracted significant attention over the past two decades for the …