Treatment of pulmonary arterial hypertension
M Humbert, O Sitbon… - New England Journal of …, 2004 - Mass Medical Soc
Pulmonary arterial hypertension, which is characterized by vascular proliferation and
remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary …
remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary …
Pulmonary arterial hypertension
PM Hassoun - New England Journal of Medicine, 2021 - Mass Medical Soc
Pulmonary Arterial Hypertension Without effective treatment, pulmonary arterial
hypertension results in high morbidity and mortality. This review discusses the pathogenesis …
hypertension results in high morbidity and mortality. This review discusses the pathogenesis …
Pulmonary arterial hypertension
LJ Rubin - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Pulmonary arterial hypertension (PAH) is a term used to classify a variety of conditions that
have in common an injury to the pulmonary vasculature that produces elevations in …
have in common an injury to the pulmonary vasculature that produces elevations in …
Pulmonary arterial hypertension: diagnosis, treatment, and novel advances
The diagnosis and management of pulmonary arterial hypertension (PAH) includes several
advances, such as a broader recognition of extrapulmonary vascular organ system …
advances, such as a broader recognition of extrapulmonary vascular organ system …
Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop
JH Newman, BL Fanburg, SL Archer, DB Badesch… - Circulation, 2004 - Am Heart Assoc
likely responsible for most cases of PAH. The abnormal transduction of signals related to
BMPR2 and Alk/endoglin is unknown and needs aggressive investigation. This will involve …
BMPR2 and Alk/endoglin is unknown and needs aggressive investigation. This will involve …
Diagnosis and treatment of pulmonary arterial hypertension: a review
NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …
Clinical trial design and new therapies for pulmonary arterial hypertension
O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
[HTML][HTML] Evaluation and management of pulmonary arterial hypertension
Pulmonary arterial hypertension is a devastating progressive disease mediated by different
pathophysiologic pathways that result in progressive increase in pulmonary vascular …
pathophysiologic pathways that result in progressive increase in pulmonary vascular …
Pulmonary hypertension: types and treatments
LJ Rose-Jones, VV Mclaughlin - Current cardiology reviews, 2015 - ingentaconnect.com
Pulmonary arterial hypertension (PAH) is a panvasculopathy that affects the distal
pulmonary arteries and leads to restricted blood flow. This increased afterload leads to …
pulmonary arteries and leads to restricted blood flow. This increased afterload leads to …
Current and future treatments of pulmonary arterial hypertension
N Sommer, HA Ghofrani, O Pak… - British journal of …, 2021 - Wiley Online Library
Therapeutic options for pulmonary arterial hypertension (PAH) have increased over the last
decades. The advent of pharmacological therapies targeting the prostacyclin, endothelin …
decades. The advent of pharmacological therapies targeting the prostacyclin, endothelin …