Treatment of pulmonary arterial hypertension

M Humbert, O Sitbon… - New England Journal of …, 2004 - Mass Medical Soc
Pulmonary arterial hypertension, which is characterized by vascular proliferation and
remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary …

Pulmonary arterial hypertension

PM Hassoun - New England Journal of Medicine, 2021 - Mass Medical Soc
Pulmonary Arterial Hypertension Without effective treatment, pulmonary arterial
hypertension results in high morbidity and mortality. This review discusses the pathogenesis …

Pulmonary arterial hypertension

LJ Rubin - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Pulmonary arterial hypertension (PAH) is a term used to classify a variety of conditions that
have in common an injury to the pulmonary vasculature that produces elevations in …

Pulmonary arterial hypertension: diagnosis, treatment, and novel advances

BA Maron, SH Abman, CG Elliott, RP Frantz… - American journal of …, 2021 - atsjournals.org
The diagnosis and management of pulmonary arterial hypertension (PAH) includes several
advances, such as a broader recognition of extrapulmonary vascular organ system …

Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop

JH Newman, BL Fanburg, SL Archer, DB Badesch… - Circulation, 2004 - Am Heart Assoc
likely responsible for most cases of PAH. The abnormal transduction of signals related to
BMPR2 and Alk/endoglin is unknown and needs aggressive investigation. This will involve …

Diagnosis and treatment of pulmonary arterial hypertension: a review

NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …

Clinical trial design and new therapies for pulmonary arterial hypertension

O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …

[HTML][HTML] Evaluation and management of pulmonary arterial hypertension

S Beshay, S Sahay, M Humbert - Respiratory Medicine, 2020 - Elsevier
Pulmonary arterial hypertension is a devastating progressive disease mediated by different
pathophysiologic pathways that result in progressive increase in pulmonary vascular …

Pulmonary hypertension: types and treatments

LJ Rose-Jones, VV Mclaughlin - Current cardiology reviews, 2015 - ingentaconnect.com
Pulmonary arterial hypertension (PAH) is a panvasculopathy that affects the distal
pulmonary arteries and leads to restricted blood flow. This increased afterload leads to …

Current and future treatments of pulmonary arterial hypertension

N Sommer, HA Ghofrani, O Pak… - British journal of …, 2021 - Wiley Online Library
Therapeutic options for pulmonary arterial hypertension (PAH) have increased over the last
decades. The advent of pharmacological therapies targeting the prostacyclin, endothelin …