The administration of bradykinin may attenuate ischemia and reperfusion (I/R) injury by
acting on B 2 Rs. Blockade of B 2 R has also been shown to ameliorate lesions associated …

Bradykinin (BK) appears to play an important role in the development and maintenance of
inflammation. Here, we assessed the role of the BK B2 receptor for the injuries that occur …

Bradykinin B1 receptors are exclusively expressed in inflamed tissues. For this reason, they
have been related with the outcomes of several pathologies. Ischemia–reperfusion injury is …

The bradykinin B1 receptor (B1R) is normally absent under physiological conditions, but is
highly inducible during inflammatory conditions or following tissue damage. The present …

B1 kinin receptor (B1R) is up-regulated by endotoxins and thus may represent a therapeutic
target in sepsis. We investigated the expression and role of B1R and B2R in the acute phase …

Previously we have demonstrated that bradykinin B1 receptor deficient mice (B1KO) were
protected against renal ischemia and reperfusion injury (IRI). Here, we aimed to analyze the …

We demonstrated that rat kinin B 1 receptors displayed a ligand-independent constitutive
activity, assessed through inositol phosphate production in transiently or stably transfected …

To explore the role of the kallikrein–kinin system in relation to ischemia/reperfusion injury in
the kidney, we generated mice lacking both the bradykinin B1 and B2 receptor genes …

Bradykinin is a mediator of inflammation, responsible for pain, vasodilation, and capillary
permeability. Bradykinin receptor 1 (B1R) and bradykinin receptor 2 (B2R) are G protein …

Inhibition of the bradykinin B2 receptor type (B2R) has been shown to improve neurological
outcome in models of focal traumatic brain injury. However, the involvement of B2R in …