Background Previous studies have shown that obesity is characterized by a sympathetic
overactivity coupled with an insulin resistance state and a baroreflex impairment. The …

Previous studies have shown that essential hypertension and obesity are both characterized
by sympathetic activation coupled with a baroreflex impairment. The present study was …

Obesity is associated with alterations in the autonomic nervous system that may contribute to
the increase in blood pressure and resting energy expenditure present in this condition. To …

Background—Previous studies have shown that sympathetic cardiovascular outflow is
increased in obese normotensive subjects and that this increase is associated with a …

Human obesity is characterized by profound alterations in the hemodynamic and metabolic
states. Whether these alterations involve sympathetic drive is controversial. In 10 young …

Objective Two hypotheses concerning mechanisms of weight gain and of blood pressure
elevation in obesity were tested. The first hypothesis is that in human obesity sympathetic …

Background Obesity and high blood pressure (BP) commonly coexist in patients, and both
conditions are associated with elevated sympathetic nervous activity. We tested whether the …

We tested the hypothesis that modest, overfeeding-induced weight gain would increase
sympathetic neural activity in nonobese humans. Twelve healthy males (23±2 years; body …

Nerve traffic recordings (muscle sympathetic nerve traffic [MSNA]) have shown that
sympathetic activation may occur in obesity. However, the small sample size of the available …

Background Disturbed sympathetic nervous function may be of importance in obesity;
sympathetic underactivity could contribute to deficient thermogenesis, positive energy …