Newly synthesised proteins need to fold, often to intricate and close-packed structures, in
order to function. The underlying mechanism by which this complex process takes place …

This review summarises our current understanding of the underlying and universal
mechanism by which newly synthesised proteins achieve their biologically functional states …

Over the past 25 years, enormous breakthroughs have been made in understanding protein
folding mechanisms. We have now reached an exciting stage, with consensuses beginning …

Protein misfolding is the underlying cause of many highly debilitating disorders ranging from
Alzheimer's Disease to Cystic Fibrosis. Great strides have been made recently in …

). Not only will a solution to the folding problem complete our knowledge of the series of
events that link a gene sequence and the three-dimensional structure of a protein, but it …

The ability of proteins to fold to their functional states following synthesis in the intracellular
environment is one of the most remarkable features of biology. Substantial progress has …

Proteins carry out many vital cellular functions determined by their precise 3-dimensional
structures (the native conformations). Understanding how proteins fold has long been a …

The ability of newly synthesised protein chains to fold into their functional conformations has
evolved within the complex intracellular environment. Until recently, however, this ability has …

The ability of proteins to fold to their functional states following synthesis in the intracellular
environment is one of the most remarkable features of biology. Substantial progress has …

The workshop was held at St Catherine's College, Oxford, from March 25–28, 1998, and
attracted participants from 32 nations. Protein folding is one of the most important processes …