Association of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)

S Mundhada, R Luthra, P Cano - BMC cancer, 2004 - Springer
Background Based on the site of breakpoint in t (9; 22)(q34; q11), bcr-abl fusion in leukemia
patients is associated with different types of transcript proteins. In this study we have seen …

[HTML][HTML] Association of HLA antigens and BCR-ABL transcripts in leukemia patients with the Philadelphia chromosome

DL Carvalho, CD Barbosa, AL Carvalho… - Revista Brasileira de …, 2012 - SciELO Brasil
OBJECTIVE: This study aimed to verify the association between human leukocyte antigens
and the bcr-abl fusion protein resulting from t (9; 22)(q34; q11) in chronic leukemia myeloid …

HLA-B8 and HLA-A3 coexpressed with HLA-B8 are associated with a reduced risk of the development of chronic myeloid leukemia

EFM Posthuma, JHF Falkenburg… - Blood, The Journal …, 1999 - ashpublications.org
Chronic myeloid leukemia (CML) is characterized by the chromosomal translocation t (9; 22)
resulting in the chimeric bcr-abl oncogene that encodes the P210 fusion protein, which …

[HTML][HTML] The Frequency of BCR-ABL1 Fusion Transcripts in Iranian Patients with Three Different Types of Leukemia

M Hamid, H Bokharaei - Zahedan Journal of Research in Medical …, 2017 - zjrms.com
Background: Different BCR-ABL fusion transcripts occur more or less frequently, in three
different types of leukemia Objectives: This study was done to determine the frequencies of …

HLA-DR4 is associated with a diminished risk of the development of chronic myeloid leukemia (CML)

EFM Posthuma, JHF Falkenburg, JF Apperley… - Leukemia, 2000 - nature.com
CML is characterized by the chromosomal translocation t (9; 22)(q34; q11) resulting in the
chimeric bcr-abl oncogene that encodes P210 fusion proteins with novel amino acid …

[HTML][HTML] Impact of the type of the BCR-ABL fusion transcript on the molecular response in pediatric patients with chronic myeloid leukemia

M Suttorp, C Thiede, JT Tauer, U Range… - …, 2010 - ncbi.nlm.nih.gov
We read with interest the article by Lucas et al. in this Journal focussing on the impact of the
BCR-ABL transcript type (e13a2 versus e14a2) in newly diagnosed patients with chronic …

Association of gene HLA-class I with leukemia

D Li, B Xi, HY Liu, Y Yu - Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2005 - europepmc.org
This study was aimed to investigate the corelation between the HLA (human leukocyte
antigen) genes and susceptibility of leukeamia. 605 patients with leukeamia including 189 …

Correlation of BCR/ABL transcript variants with patients' characteristics in childhood chronic myeloid leukaemia

R Adler, S Viehmann, E Kuhlisch… - European journal of …, 2009 - Wiley Online Library
Background and objective: The characteristic chromosomal translocation t (9; 22)(q34; q11)
in chronic myeloid leukaemia (CML) mainly results in the two different BCR/ABL fusion …

A BCR-ABL oncoprotein p210b2a2 fusion region sequence is recognized by HLA-DR2a restricted cytotoxic T lymphocytes and presented by HLA-DR matched cells …

GJA ten Bosch, JH Kessler, AM Joosten… - Blood, The Journal …, 1999 - ashpublications.org
Peptides corresponding to the fusion site in 210 kD BCR-ABL protein b3a2 (p210b3a2)
were previously shown to bind to several HLA class I and II alleles. We have found that b3a2 …

[PDF][PDF] Correlation of p210 BCR-ABL transcript variants with clinical, parameters and disease outcome in 45 chronic myeloid leukemia patients

W Al-Achkar, F Moassass, N Youssef, A Wafa - J BUON, 2016 - researchgate.net
Purpose: The aim of this study was to search the BCR/ABL 1 fusion gene in 45 chronic
myeloid leukemia (CML) Syrian patients using nested reverse transcription polymerase …