Impact of preventing exacerbations on deterioration of health status in COPD

S Spencer, PMA Calverley, PS Burge… - European respiratory …, 2004 - Eur Respiratory Soc
Exacerbations of chronic obstuctive pulmonary disease (COPD) are associated with worse
health status. The Inhaled Steroids in Obstructive Lung Disease in Europe (ISOLDE) study …

Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes

A Anzueto, I Leimer, S Kesten - International journal of chronic …, 2009 - Taylor & Francis
Background COPD exacerbations are responsible for the morbidity and mortality of this
disease. The relationship between exacerbations and patient-related clinical outcomes is …

Disease severity and the effect of fluticasone propionate on chronic obstructive pulmonary disease exacerbations

PW Jones, LR Willits, PS Burge… - European Respiratory …, 2003 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with worse
health and increased healthcare utilisation. The Inhaled Steroids in Obstructive Lung …

Exacerbation frequency and course of COPD

DMG Halpin, M Decramer, B Celli… - … journal of chronic …, 2012 - Taylor & Francis
Background Exacerbations affect morbidity in chronic obstructive pulmonary disease
(COPD). We sought to evaluate the association between exacerbation frequency and …

Negative impacts of unreported COPD exacerbations on health-related quality of life at 1 year

W Xu, JP Collet, S Shapiro, Y Lin… - European …, 2010 - Eur Respiratory Soc
Unreported chronic obstructive pulmonary disease (COPD) exacerbations are common, but
their intermediate-to-long-term impacts on health-related quality of life (HRQoL) are …

[HTML][HTML] Effect of a single exacerbation on decline in lung function in COPD

DMG Halpin, M Decramer, BR Celli, A Mueller… - Respiratory …, 2017 - Elsevier
Background COPD exacerbations are associated with accelerated lung function decline, but
whether they are causal is unknown. We evaluated the effect of a single exacerbation on …

[HTML][HTML] Effect of fluticasone propionate/salmeterol (250/50 μg) or salmeterol (50 μg) on COPD exacerbations

GT Ferguson, A Anzueto, R Fei, A Emmett, K Knobil… - Respiratory …, 2008 - Elsevier
OBJECTIVES: COPD exacerbations are associated with significant morbidity and mortality.
This randomized, double-blind, parallel-group, multicenter study evaluated the effect of …

Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a …

EFM Wouters, DS Postma, B Fokkens, WCJ Hop… - Thorax, 2005 - thorax.bmj.com
Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment
for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator …

Relationship between respiratory symptoms and medical treatment in exacerbations of COPD

P Calverley, R Pauwels, CG Löfdahl… - European …, 2005 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) can be defined
symptomatically or by healthcare contacts, yet the relationship between these events is …

Longitudinal changes in the nature, severity and frequency of COPD exacerbations

GC Donaldson, TAR Seemungal… - European …, 2003 - Eur Respiratory Soc
Exacerbations are an important feature and outcome measure in chronic obstructive
pulmonary disease (COPD), but little is known about changes in their severity, recovery …