SLC39 proteins are members of the broader ZIP family of metal ion transporters found in
organisms at all phylogenetic levels. Most ZIP transporters have eight predicted …

Fourteen members of the Slc39a superfamily of metal ion uptake transporters have been
identified in mice and humans, but the physiological functions of most remain obscure …

Cellular zinc influx and efflux are maintained by two major transporter families, the ZIP
(SLC39A) and ZnT (SLC30A or CDF) molecules. The functions of one molecule in this class …

The mouse and human Zip5 proteins are members of the ZIP family of metal ion
transporters. In this study, we present evidence that mouse Zip5 is a zinc uptake transporter …

Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …

The solute carriers families 30 (SLC30; ZnT), 39 (SLC39; ZIP), and 31 (SLC31; CTR) are
involved in the essential maintenance of cellular zinc (Zn 2+) and copper (Cu 2+) …

Zip14 is a member of the SLC39A zinc transporter family, which is involved in zinc uptake by
cells. Up-regulation of Zip14 by IL-6 appears to contribute to the hepatic zinc accumulation …

The SLC39A family of zinc transporters can be divided into four subfamilies (I, II, LIV-1, and
gufA) in vertebrates, but studies of their functions have been restricted exclusively to …

The SLC39A family of metal transporters was identified through homologies with the Zrt-and
Irt-like (ZIP) proteins from yeast and plants. Of all the ZIP transporters, ZIP14 is arguably the …

ZIP8 (SLC39A8) belongs to the ZIP family of metal-ion transporters. Among the ZIP proteins,
ZIP8 is most closely related to ZIP14, which can transport iron, zinc, manganese, and …