toward lung regions with better ventilation and a higher intraalveolar partial pressure of
oxygen. Inhaled NO enhances this mechanism by increasing blood flow to well-ventilated …

Inhalation of nitric oxide (NO), an endoge‐neous vasodilator, was recently described to
reduce pulmonary vascular resistance, and to improve arterial oxygenation by selective …

Nitric oxide (NO) is a gas that induces relaxation of smooth muscle cells in the vasculature.
Because NO reacts with oxyhaemoglobin with high affinity, the gas is rapidly scavenged by …

Objective To determine the dose-response curve of inhaled nitric oxide (NO) in terms of
pulmonary vasodilation and improvement in PaO 2 in adults with severe acute respiratory …

Abbreviations: BPF= bronchopleural fistula; cGMP= guanylate cyclase/guanosine 3', 5'-
cyclic monophosphate; eNOS= constitutive NOS; ECMO= extracorporeal membrane …

Purpose Although the analogy of nitric oxide (NO) to Endothelium-derived Relaxing Factor
remains controversial, medical use of exogenous NO gas by inhalation has grown …

Nitric oxide (NO) is an endogenous endothelium-derived relaxing factor that participates in
the regulation of vascular tone. We studied the effects of inhaled NO gas on transient …

In the lung, nitric oxide (NO) derives from several cellular sources, forming networks of
paracrine communication. In pulmonary vessels, NO produced by endothelial cells is a …

Background The adult respiratory distress syndrome is characterized by pulmonary
hypertension and right-to-left shunting of venous blood. We investigated whether inhaling …

Nitric oxide (NO) is an endogenous mediator of vascular tone and host defence. Inhaled
nitric oxide (iNO) results in preferential pulmonary vasodilatation and lowers pulmonary …