Galanin receptor subtype GalR2 mediates apoptosis in SH-SY5Y neuroblastoma cells
A Berger, R Lang, K Moritz, R Santic, A Hermann… - …, 2004 - academic.oup.com
Recently we have shown that galanin binding significantly correlates with survival in
neuroblastoma patients, indicating a possible modulatory role of galanin receptors in …
neuroblastoma patients, indicating a possible modulatory role of galanin receptors in …
Galanin and galanin receptor expression in neuroblastic tumours: correlation with their differentiation status
Y Perel, L Amrein, E Dobremez, J Rivel… - British journal of …, 2002 - nature.com
Neuroblastoma and its benign differentiated counterpart, ganglioneuroma, are paediatric
neuroblastic tumours arising in the sympathetic nervous system. Their broad spectrum of …
neuroblastic tumours arising in the sympathetic nervous system. Their broad spectrum of …
Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2)
Galanin is a neuropeptide with a wide range of effects in the nervous and endocrine
systems, mediated through three G protein-coupled receptor subtypes (GalR1–3) …
systems, mediated through three G protein-coupled receptor subtypes (GalR1–3) …
Elevated expression of galanin receptors in childhood neuroblastic tumors
A Berger, C Tuechler, D Almer, P Kogner… - …, 2002 - karger.com
The neuropeptide galanin (GAL) has been shown to be present in certain brain tumors. In
order to learn more about GAL and its receptors in human tumors of the peripheral nervous …
order to learn more about GAL and its receptors in human tumors of the peripheral nervous …
Galanin and galanin receptors in human cancers
A Berger, R Santic, C Hauser-Kronberger, FH Schilling… - Neuropeptides, 2005 - Elsevier
The increasing interest in peptides and peptide receptors in cancer is based on the
possibility of receptor targeting, because peptide receptors are often expressed in different …
possibility of receptor targeting, because peptide receptors are often expressed in different …
Galanin Receptor Subtype 2 Suppresses Cell Proliferation and Induces Apoptosis in p53 Mutant Head and Neck Cancer Cells
T Kanazawa, PK Kommareddi, T Iwashita, B Kumar… - Clinical Cancer …, 2009 - AACR
Purpose: Galanin and its three receptors (GALR1-3) are expressed in many normal tissues,
but silenced in some tumors. Contradictory roles for galanin and its receptors in various …
but silenced in some tumors. Contradictory roles for galanin and its receptors in various …
Galanin and galanin receptors in human gliomas
A Berger, R Santic, D Almer, C Hauser-Kronberger… - Acta …, 2003 - Springer
Galanin-like immunoreactivity (GAL-LI) and specific GAL binding sites have been shown to
be widely distributed in the central nervous system (CNS) and in CNS tumors. GAL and its …
be widely distributed in the central nervous system (CNS) and in CNS tumors. GAL and its …
Galanin receptor subtypes and ligand binding
A Florén, T Land, Ü Langel - Neuropeptides, 2000 - Elsevier
Galanin is a neuropeptide initiating its multiple biological effects by binding to different
subtypes of seven transmembrane spanning galanin receptors, thus transducing the …
subtypes of seven transmembrane spanning galanin receptors, thus transducing the …
Pharmacological and biochemical characterization of a recombinant human galanin GALR1 receptor: agonist character of chimeric galanin peptides
LW Fitzgerald, JP Patterson, DS Conklin… - … of Pharmacology and …, 1998 - ASPET
The galanin neuropeptide system is widely distributed throughout the brain and periphery
and is thought to play a role in feeding, pain and reproduction. To evaluate the human …
and is thought to play a role in feeding, pain and reproduction. To evaluate the human …
Pharmacological characterization and tissue distribution of the human and rat GALR1 receptors
KA Sullivan, LL Shiao, MA Cascieri - Biochemical and biophysical research …, 1997 - Elsevier
The diverse biological functions of galanin are mediated via membrane bound high-affinity
receptors. In order to identify and characterize potential galanin receptor subtypes, we have …
receptors. In order to identify and characterize potential galanin receptor subtypes, we have …