Identification of amino‐terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration

T Arai, K Ikeda, H Akiyama, T Nonaka… - Annals of Neurology …, 2004 - Wiley Online Library
Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are
neurodegenerative diseases that are characterized by intracytoplasmic aggregates of …

Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration

DW Dickson - Journal of neurology, 1999 - Springer
Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are usually
sporadic multisystem degenerations associated with filamentous tau inclusions in neurons …

Progressive supranuclear palsy and corticobasal degeneration

DW Dickson - Functional neurobiology of aging, 2001 - Elsevier
Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic
neurodegenerative disorders of mid to late adult life that have shared clinical and pathologic …

Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy

MB Feany, H Ksiezak-Reding, WK Liu, I Vincent… - Acta …, 1995 - Springer
Corticobasal degeneration (CBD) is a rare, progressive neurological disorder characterized
by widespread neuronal and glial accumulation of abnormal tau protein. Using …

Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: Expansion of the disease phenotype caused by tau gene …

PM Stanford, GM Halliday, WS Brooks, JBJ Kwok… - Brain, 2000 - academic.oup.com
Genetic mutations in the tau gene on chromosome 17 are known to cause frontotemporal
dementias. We have identified a novel silent mutation (S305S) in the tau gene in a subject …

Cerebellar cortical tau pathology in progressive supranuclear palsy and corticobasal degeneration

YS Piao, S Hayashi, K Wakabayashi, A Kakita… - Acta …, 2002 - Springer
Immunohistochemical localization of tau in the cerebellar cortex was carried out using a
mouse monoclonal antibody against phosphorylation-dependent tau (AT8) in brain tissue …

Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype

H Houlden, M Baker, HR Morris, N MacDonald… - Neurology, 2001 - AAN Enterprises
Objective: To analyze the association of polymorphisms in the tau gene with pathologically
confirmed corticobasal degeneration (CBD). Background: The authors previously described …

Corticobasal degeneration shares a common genetic background with progressive supranuclear palsy

E Di Maria, M Tabaton, T Vigo… - Annals of Neurology …, 2000 - Wiley Online Library
Corticobasal degeneration is a sporadic form of tauopathy, involving the cerebral cortex and
extrapyramidal motor system. A series of affected subjects was genotyped for a set of …

Atypical progressive supranuclear palsy with corticospinal tract degeneration

KA Josephs, O Katsuse… - … of Neuropathology & …, 2006 - academic.oup.com
Progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), sporadic
multisystem tauopathy, and some forms of frontotemporal dementia with Parkinsonism …

Relationship of the extended tau haplotype to tau biochemistry and neuropathology in progressive supranuclear palsy

WK Liu, TV Le, J Adamson, M Baker… - Annals of Neurology …, 2001 - Wiley Online Library
Two extended haplotypes of the tau gene (H1 and H2) have been described. The frequency
of H1 haplotype is increased in progressive supranuclear palsy (PSP). PSP is associated …