The objective of this study was to assess the contributions of surfactant-mediated solubility
and micellar diffusivity on the ability of surfactant to enhance drug dissolution. The following …

Abstract□ The in vivo dissolution of many poorly soluble drugs is enhanced by the action of
surfactants secreted into the upper gastrointestinal (GI) tract. These substances may act by …

The intrinsic dissolution rate of carbamazepine in solutions of sodium lauryl sulfate was
measured to study the convective diffusion transport of drug-loaded micelles from a rotating …

A series of in vitro experiments was performed to demonstrate the interdependence of
physiologic surfactant and drug particle size on the dissolution rate of glutethimide …

The ability of surfactants to accelerate the in vitro dissolution of very slightly soluble drugs
has been ascribed to wetting and/or micellar solubilization. Deflocculation as a mechanism …

Hydrophobie matrices were prepared using Eudragit RL 100. Flurbiprofen was used as a
model drug, with sorbitol as a diluent. The effect of adding each of five surfactants (sodium …

The effects of types of surfactants on the solubilization and dissolution of poorly soluble
acidic drugs were compared to identify the most suitable surfactant for conducting an acidic …

Biorelevant dissolution media (BDM) methods are commonly employed to investigate the
oral absorption of poorly water-soluble drugs. Despite the significant progress in this area …

Mixed surfactants may improve the performance of surfactant-enhanced solubilization of
drugs and thus can serve as the tool for increased bioavalaibility, controlled drug release …

The solubility of fenofibrate in pH 6.8 McIlvaine buffers containing varying concentrations of
sodium lauryl sulfate was determined. The dissolution behavior of fenofibrate was also …