Glycyrrhetinic acid (GA) and its related compounds are known to have anti-inflammatory
activity and also to inhibit liver carcinogenesis and tumor growth. GA and related …

The following is a position paper challenging the paradigm that 'carcinogen= mutagen', and
that the current rodent bioassay to predict risks to human cancers is relevant and useful …

1 We have investigated the effects of connexin‐mimetic peptides homologous to the Gap 26
and Gap 27 domains of Cxs 37, 40 and 43 against gap junctional communication and …

Oculodentodigital dysplasia, a rare condition displaying congenital craniofacial deformities
and limb abnormalities, has been associated with over 20 known human connexin43 (Cx43) …

Extension of a burn wound over the first 24h following injury is recognised clinically, and
leads to diagnostic and therapeutic dilemmas. In the central nervous system, a similar …

The PDZ domain‐containing protein zonula occludens‐1 (ZO‐1) interacts with several
members of the connexin (Cx) family of gap junction‐forming proteins and has been …

Retinal bipolar cells are known to form a complex, interconnecting network through electrical
synapses that are either heterologous (with amacrine cells) or homologous (with other …

A gap junction is composed of two hemichannels and possesses a relatively large pore size
(∼ 10–15 Å), allowing passage of ions and molecules up to 1 kDa. Here, we report that …

The connexin43 knockout (Cx43α1 KO) mouse dies at birth from outflow obstruction
associated with infundibular pouches. To elucidate the origin of the infundibular pouches …

Cell extraction with cold nonionic detergents or alkaline carbonate prepares an insoluble
membrane fraction whose buoyant density permits its flotation in discontinuous sucrose …