Refining molecular analysis in the pathways of colorectal carcinogenesis
A Rowan, S Halford, M Gaasenbeek, Z Kemp… - Clinical …, 2005 - Elsevier
Background & Aims: In the stepwise model, specific genetic and epigenetic changes
accumulate as colorectal adenomas progress to carcinomas (CRCs). CRCs also acquire …
accumulate as colorectal adenomas progress to carcinomas (CRCs). CRCs also acquire …
[HTML][HTML] Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer
B Halvarsson, A Lindblom, L Johansson, K Lagerstedt… - Modern Pathology, 2005 - Elsevier
Colorectal adenomas occur at younger age, at increased frequency and have a greater
tendency for malignant transformation in patients with hereditary nonpolyposis colorectal …
tendency for malignant transformation in patients with hereditary nonpolyposis colorectal …
Tracing origin of serrated adenomas with BRAF and KRAS mutations
Serrated neoplasm of the colorectum raised many as-yet unanswered issues. To
characterize serrated neoplasia pathway, we investigated BRAF and KRAS mutations in 35 …
characterize serrated neoplasia pathway, we investigated BRAF and KRAS mutations in 35 …
Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous …
DH Kim, JW Kim, JH Cho, SH Baek… - International …, 2005 - spandidos-publications.com
Mucin core proteins are expressed in a tissue and cell type specific manner in the normal
gastrointestinal tract. Aberrant expression of mucin core proteins have been reported in …
gastrointestinal tract. Aberrant expression of mucin core proteins have been reported in …
[PDF][PDF] Clinical significance of (sessile) serrated adenomas: another piece of the puzzle
NS Goldstein - American journal of clinical pathology, 2005 - Citeseer
Serrated polyps of the colon have been the focus of critical reappraisal and intense study
over the past several years. Until recently, most serrated, nonadenomatous polyps were …
over the past several years. Until recently, most serrated, nonadenomatous polyps were …
New targets and new drugs down under in 2004.
SA Doggrell - Drug News & Perspectives, 2005 - europepmc.org
The Second Australian Health and Medical Research Congress, held November 21-26,
2004, in Sydney, Australia, brought together 28 specialist societies across a broad range of …
2004, in Sydney, Australia, brought together 28 specialist societies across a broad range of …
[图书][B] Molecular genetic studies of colorectal cancer
XL Zhou - 2005 - search.proquest.com
Colorectal cancer (CRC) is one of the leading causes of morbidity and mortality due to
cancer in the Western countries. Epidemiological studies have shown that at least 20-30% of …
cancer in the Western countries. Epidemiological studies have shown that at least 20-30% of …
[PDF][PDF] Molecular classification of colorectal cancer
P Laiho - 2005 - helda.helsinki.fi
Colorectal cancer (CRC) is the third most common cancer in the Western countries. Some
genetic alterations behind the colorectal tumor progression are well known, such as loss of …
genetic alterations behind the colorectal tumor progression are well known, such as loss of …
[HTML][HTML] Classification moleculaire des patients ayant une polypose hamartomateuse ou hyperplasique
K Sweet, J Willis, XP Zhou, C Gallione… - JAMA …, 2005 - triggered.clockss.org
Contexte Des pourcentages significatifs de patients atteints de polypose hamartomateuse
ou dysembryoplasique ou ayant une polypose hyperplasique/mixte demeurent sans …
ou dysembryoplasique ou ayant une polypose hyperplasique/mixte demeurent sans …
大腸癌におけるKRAS, BRAF 遺伝子突然変異とDNA メチル化
永坂岳司， 松原長秀， 笹本博美， 高畑隆臣… - 岡山医学会 …, 2005 - jstage.jst.go.jp
この約 10 年 間にお いて遺伝 子情報 に関す る研 究は飛躍的な進歩 を示 した. そ の一つには, 全
ヒューマ ンゲノム (実 際は 98.8%) が 解読 された として, 2003 年 4 月 14 日 に ヒューマ ンゲ …
ヒューマ ンゲノム (実 際は 98.8%) が 解読 された として, 2003 年 4 月 14 日 に ヒューマ ンゲ …