Periadolescent nicotine administration produces enduring changes in dendritic morphology of medium spiny neurons from nucleus accumbens

CG McDonald, VK Dailey, HC Bergstrom, TL Wheeler… - Neuroscience …, 2005 - Elsevier
The objective of the current study was to examine how periadolescent nicotine exposure
affects dendritic morphology of medium spiny neurons from the nucleus accumbens shell …

The role of tissue plasminogen activator in methamphetamine‐related reward and sensitization

T Nagai, Y Noda, K Ishikawa, Y Miyamoto… - Journal of …, 2005 - Wiley Online Library
In the central nervous system, tissue plasminogen activator (tPA) plays a role in synaptic
plasticity and remodeling. Our recent study has suggested that tPA participates in the …

Changes in gene expression within the nucleus accumbens and striatum following sexual experience

KC Bradley, MB Boulware, H Jiang… - Genes, Brain and …, 2005 - Wiley Online Library
Sexual experience, like repeated drug use, produces long‐term changes including
sensitization in the nucleus accumbens and dorsal striatum. To better understand the …

Pleiotrophin gene transcription in the rat nucleus accumbens is stimulated by an acute dose of amphetamine

P Le Grevès - Brain research bulletin, 2005 - Elsevier
Pleiotrophin (PTN) is a heparin-binding protein with diverse functions. For example, it
stimulates neurite outgrowth, mitogenesis, repair and differentiation, effects that are similar …

Ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats

MJ Hunt, K Kessal, R Garcia - Journal of Neuroscience, 2005 - Soc Neuroscience
Noncompetitive NMDA receptor antagonists, such as ketamine, induce a transient
schizophrenia-like state in healthy individuals and exacerbate psychosis in schizophrenic …

Increases in the density of parvalbumin-immunoreactive neurons in anterior cingulate cortex of amphetamine-withdrawn rats: evidence for corticotropin-releasing …

CA Mohila, SP Onn - Cerebral Cortex, 2005 - academic.oup.com
We previously reported synchronization of pyramidal neurons within prefrontal cortex of rats
repeatedly exposed to amphetamine (AMPH). To test the hypothesis that cortical …

Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats

M Narita, H Akai, T Kita, Y Nagumo, N Sunagawa… - Neuroscience, 2005 - Elsevier
The neural plasticity associated with behavioral sensitization following repeated
administration of a psychostimulant methamphetamine (METH) is thought to require …

Different effects of valproate on methamphetamine-and cocaine-induced behavioral sensitization in mice

JX Li, R Han, YP Deng, SQ Chen, JH Liang - Behavioural brain research, 2005 - Elsevier
Repetitive exposure to psychostimulants elicits behavioral sensitization. Accumulating
evidence have shown that the central GABAergic system is involved in psychostimulants …

[引用][C] 阿片成瘾的细胞分子机制

陈晓岚, 刘景根, 池志强 - 中国药理学通报, 2005

A single exposure to novelty differentially affects the accumbal dopaminergic system of apomorphine-susceptible and apomorphine-unsusceptible rats

MCJ van der Elst, MMM Verheij, EW Roubos… - Life sciences, 2005 - Elsevier
Individual differences in responses to mild, acute stressors in laboratory animals have
commonly been observed in behavioural tests and at the level of hypothalamic-pituitary …