Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection

CR Wira, KS Grant‐Tschudy… - American journal of …, 2005 - Wiley Online Library
The continued presence of bacterial and viral antigens in the lumen of the vagina coupled
with the periodic presence of antigens in the lumena of the upper reproductive tract provide …

Innate immunity in the female reproductive tract: role of sex hormones in regulating uterine epithelial cell protection against pathogens

DO Ochiel, JV Fahey, M Ghosh… - Current women's …, 2008 - ingentaconnect.com
The mucosal immune system in the upper female reproductive tract is uniquely prepared to
maintain a balance between the presence of commensal bacteria, sexually transmitted …

Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: stratification and integration of immune protection against the transmission of …

DK Hickey, MV Patel, JV Fahey, CR Wira - Journal of reproductive …, 2011 - Elsevier
This review examines the multiple levels of pre-existing immunity in the upper and lower
female reproductive tract. In addition, we highlight the need for further research of innate and …

The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells

AJ Quayle - Journal of reproductive immunology, 2002 - Elsevier
The female reproductive tract is immunologically unique in its requirement for tolerance to
allogeneic sperm and, in the upper tract, to the conceptus. However, it must also be …

Innate and adaptive immunity in female genital tract: cellular responses and interactions

CR Wira, JV Fahey, CL Sentman, PA Pioli… - Immunological …, 2005 - Wiley Online Library
The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

Immunology of the uterine and vaginal mucosae

JZ Zhou, SS Way, K Chen - Trends in immunology, 2018 - cell.com
Along with the maintenance of symbiotic mutualism with commensal microbes and
protection against invasive infections common to all mucosal barrier tissues, female …

Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against …

CR Wira, JV Fahey, M Ghosh, MV Patel… - American journal of …, 2010 - Wiley Online Library
Citation Wira CR, Fahey JV, Ghosh M, Patel MV, Hickey DK, Ochiel DO. Sex hormone
regulation of innate immunity in the female reproductive tract: the role of epithelial cells in …

[HTML][HTML] Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture

JV Fahey, JA Wright, L Shen, JM Smith, M Ghosh… - Mucosal …, 2008 - Elsevier
The goal of this study was to examine the role of E 2 in regulating innate immune protection
by human uterine epithelial cells (UECs). Recognizing that UECs produce cytokines and …

Innate immunity in the human endometrium and ovary

IM Sheldon, JJ Bromfield - American journal of reproductive …, 2011 - Wiley Online Library
Citation Sheldon IM, Bromfield JJ. Innate Immunity in the Human Endometrium and Ovary.
Am J Reprod Immunol 2011; 66 (Suppl. 1): 63–71 Problem Microbial infections of the upper …

[HTML][HTML] Immune cells in the female reproductive tract

SK Lee, CJ Kim, DJ Kim, J Kang - Immune network, 2015 - synapse.koreamed.org
The female reproductive tract has two main functions: protection against microbial challenge
and maintenance of pregnancy to term. The upper reproductive tract comprises the fallopian …