Dendritic cells (DCs) regulate various aspects of innate immunity, including natural killer
(NK) cell function. Here we define the mechanisms involved in DC–NK cell interactions …

Dendritic cells (DC), first characterized in 1973 by Steinman and Cohn, have been defined
as the professional antigen presenting cells (APC), capable of activating naïve T cells much …

Natural killer (NK) cells and dendritic cells (DCs) are, respectively, central components of
innate and adaptive immune responses,. We describe here a third DC lineage, termed …

Natural killer (NK) cells are important effector cells in the control of infections. The cellular
and molecular signals required for NK cell activation in vivo remain poorly defined. By using …

Natural interferon-producing cells (IPC) respond to viruses by secreting type I interferon
(IFN) and interleukin-12 (IL-12). Toll-like receptor (TLR) 9 mediates IPC recognition of some …

NK cells are key regulators of innate defense against mouse CMV (MCMV). Like NK cells,
NKT cells also produce high levels of IFN-γ rapidly after MCMV infection. However, whether …

Dendritic cells (DCs) are professional antigen-presenting cells, which display an
extraordinary capacity to induce T-cell responses. Recent findings revealed that DCs also …

Infections with HIV, hepatitis B virus, and hepatitis C virus can turn into chronic infections,
which currently affect more than 500 million patients worldwide. It is generally thought that …

Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the
cellular and molecular mechanisms are not fully understood. Using an optimized humanized …

Conserved molecular patterns derived from pathogenic microorganisms prime antigen-
presenting dendritic cells (DC) to induce adaptive T cell responses. In contrast, virus …