Insulin resistance is frequently accompanied by obesity and both obesity and type 2
diabetes are associated with a mild chronic inflammation. Elevated levels of various …

The peroxisome proliferator-activated receptor gamma (PPARγ), a member of the nuclear
hormone receptor superfamily has classically been characterized for its implications in …

The nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPARγ)
is a member of the PPAR family. The endogenous activators of all members of the PPAR …

Context: Adipose tissue is a metabolically dynamic organ, serving as a buffer to control fatty
acid flux and a regulator of endocrine function. In obese subjects, and those with type 2 …

Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
exerting several functions in development and metabolism. PPARα, activated by …

Drugs that reverse insulin resistance are of importance as insulin resistance is frequently
associated with type 2 diabetes. The three peroxisome proliferator-activated receptors …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor isoforms with key
roles in the regulation of lipid and glucose metabolism. Synthetic ligands for PPARγ (and …

PPARγ activation in type 2 diabetic patients results in a marked improvement in insulin and
glucose parameters, resulting from an improvement of whole‐body insulin sensitivity …

It is currently thought that the effects of PPARγ activation on glucose homeostasis may be
due to the effect of this nuclear receptor on the production of adipocyte-derived signalling …

Peroxisome proliferator-activated receptors (PPAR) belong to the nuclear receptor
superfamily of ligand-activated transcription factors. PPAR-α, first of its three subtypes (α, β …