Measuring the metabolome: current analytical technologies

WB Dunn, NJC Bailey, HE Johnson - Analyst, 2005 - pubs.rsc.org
The post-genomics era has brought with it ever increasing demands to observe and
characterise variation within biological systems. This variation has been studied at the …

Metabolomics: current technologies and future trends

K Hollywood, DR Brison, R Goodacre - Proteomics, 2006 - Wiley Online Library
The ability to sequence whole genomes has taught us that our knowledge with respect to
gene function is rather limited with typically 30–40% of open reading frames having no …

Metabolomics and its use in ecology

OAH Jones, ML Maguire, JL Griffin, DA Dias… - Austral …, 2013 - Wiley Online Library
Metabolomics may be defined as the analysis of thousands of naturally occurring small
molecules (metabolites) such as sugars, organic acids, amino acids and nucleotides that are …

Analytical metabolomics and applications in health, environmental and food science

M Fraga-Corral, M Carpena… - Critical Reviews in …, 2022 - Taylor & Francis
Metabolomics is a young field of knowledge that arises linked to other omics such as
genomics, transcriptomics, and proteomics. This discipline seeks to understand the …

Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes

WB Dunn - Physical biology, 2008 - iopscience.iop.org
The functional levels of biological cells or organisms can be separated into the genome,
transcriptome, proteome and metabolome. Of these the metabolome offers specific …

Metabolomics: an emerging post-genomic tool for nutrition

PD Whitfield, AJ German, PJM Noble - British Journal of Nutrition, 2004 - cambridge.org
The post-genomic era has been driven by the development of technologies that allow the
function of cells and whole organisms to be explored at the molecular level. Metabolomics is …

Current metabolomics: practical applications

SP Putri, Y Nakayama, F Matsuda, T Uchikata… - Journal of bioscience …, 2013 - Elsevier
The field of metabolomics continues to grow rapidly over the last decade and has been
proven to be a powerful technology in predicting and explaining complex phenotypes in …

Metabolomics—The state of art

A Krastanov - Biotechnology & Biotechnological Equipment, 2010 - Taylor & Francis
Metabolomics is an emerging field of “omics” research that focuses on high-throughput
characterization of small molecule metabolites in biological matrices. This review focuses on …

Towards quantitative mass spectrometry-based metabolomics in microbial and mammalian systems

RV Kapoore, S Vaidyanathan - … Transactions of the …, 2016 - royalsocietypublishing.org
Metabolome analyses are a suite of analytical approaches that enable us to capture
changes in the metabolome (small molecular weight components, typically less than 1500 …

Metabolomics reviewed: a new “omics” platform technology for systems biology and implications for natural products research

S Rochfort - Journal of natural products, 2005 - ACS Publications
Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism)
under a given set of conditions. The analysis of the metabolome is particularly challenging …