Similar to several other viruses, human T cell leukemia virus type I (HTLV-I) induces the
formation of multinucleated giant cells (also known as syncytium) when amplified in tissue …

Infection by human T-cell leukemia viruses (HTLV-I and HTLV-II) induces syncytium
formation in certain cell typesin vitro. Recombinant vaccinia viruses expressing the HTLV-II …

We constructed a sensitive and quantitative assay system to examine human T-cell
leukemia virus type I (HTLV-I) envelope (env) glycoprotein-mediated cell fusion in which T7 …

Objective: Identifying the new integration of human T-lymphotropic virus type I (HTLV-I)
proviral genome into initially uninfected cells after cocultivation with HTLV-I infected cells is …

HTLV-1 cellular transformation and disease induction is dependent on expression of the
viral Tax oncoprotein. PDZ is a modular protein interaction domain used in organizing …

An important increase in luciferase activity was detected following co-culture of Jurkat T cells
transiently transfected with an HTLV-I-LTR-driven reporter construct with HIV-1-and HTLV-I …

Abstract HTLV-1 and HTLV-2 viruses express Tax transactivator proteins required for viral
genome transcription and capable of transforming cells in vivo and in vitro. Although Tax …

Human T cell leukemia virus type 1 (HTLV-1) causes two major diseases: adult T-cell
leukemia-lymphoma and tropical spastic paraparesis/HTLV-1 associated myelopathy …

The exact mechanism by which the human T cell leukemia viruses (HTLV) infects target cells
remains unclear; although some molecules have been identified to be important in viral …

Tax protein of HTLV-1 triggers transcriptional activation through enhancers, NF-κB binding
site, 21-bp enhancer, and serum response element. Previously, we demonstrated binding of …