The evolution of the neocortex in mammals: how is phenotypic diversity generated?

L Krubitzer, J Kaas - Current opinion in neurobiology, 2005 - Elsevier
Evolution of the mammalian neocortex is difficult to examine directly. For this reason,
comparative studies and developmental studies are the best way of gaining insight into the …

Arealization of the neocortex in mammals: genetic and epigenetic contributions to the phenotype

L Krubitzer, KJ Huffman - Brain Behavior and Evolution, 2000 - karger.com
The neocortex is composed of areas that are functionally, anatomically and histochemically
distinct. In comparison to most other mammals, humans have an expanded neocortex, with a …

How does evolution build a complex brain?

LA Krubitzer - … Developmental Biology of the Cerebral Cortex …, 2000 - Wiley Online Library
To understand how complex brains evolve one can examine a variety of the products of the
evolutionary process and then infer the mechanisms that generate the differences observed …

The combinatorial creature: cortical phenotypes within and across lifetimes

LA Krubitzer, TJ Prescott - Trends in neurosciences, 2018 - cell.com
The neocortex is one of the most distinctive structures of the mammalian brain, yet also one
of the most varied in terms of both size and organization. Multiple processes have …

In search of a unifying theory of complex brain evolution

L Krubitzer - Annals of the New York Academy of Sciences, 2009 - Wiley Online Library
The neocortex is the part of the brain that is involved in perception, cognition, and volitional
motor control. In mammals it is a highly dynamic structure that has been dramatically altered …

Genetic mechanisms underlying cortical evolution in mammals

LF Franchini - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
The remarkable sensory, motor, and cognitive abilities of mammals mainly depend on the
neocortex. Thus, the emergence of the six-layered neocortex in reptilian ancestors of …

The organization of neocortex in mammals: are species differences really so different?

L Krubitzer - Trends in neurosciences, 1995 - cell.com
Throughout THE ZOTH CENTURY, remarkable advances in techniques for studying the
brain have revealed that the neocortex comprises a number of functional parts that …

Evolution and development of the mammalian cerebral cortex

Z Molnár, JH Kaas, JA De Carlos, RF Hevner… - Brain Behavior and …, 2014 - karger.com
Comparative developmental studies of the mammalian brain can identify key changes that
can generate the diverse structures and functions of the brain. We have studied how the …

How unique is the human neocortex?

Z Molnár, A Pollen - 2014 - journals.biologists.com
The human cerebral cortex is generally considered the most complex organ, and is the
structure that we hold responsible for the repertoire of behavior that distinguishes us from …

Evolutionary specialization in mammalian cortical structure

RA Barton - Journal of evolutionary biology, 2007 - academic.oup.com
Abstract Changes in neocortex size were a prominent feature of mammalian brain evolution,
but the implications for cortical structure, and consequently for the functional significance of …