Olfactory ensheathing cells and spinal cord repair

A Mackay-Sim - The Keio journal of medicine, 2005 - jstage.jst.go.jp
The olfactory ensheathing cell is a specialized glial cell that assists in growth of the axons of
the olfactory sensory neurons as they are generated and regenerated throughout adult life …

Olfactory ensheathing cells from the nose: clinical application in human spinal cord injuries

A Mackay-Sim, JA St John - Experimental neurology, 2011 - Elsevier
Olfactory mucosa, the sense organ of smell, is an adult tissue that is regenerated and
repaired throughout life to maintain the integrity of the sense of smell. When the sensory …

Olfactory ensheathing cells—another miracle cure for spinal cord injury?

G Raisman - Nature Reviews Neuroscience, 2001 - nature.com
Several recent publications describe remarkably promising effects of transplanting olfactory
ensheathing cells as a potential future method to repair human spinal cord injuries. But why …

Olfactory ensheathing cells: their potential use for repairing the injured spinal cord

J Lu, K Ashwell - Spine, 2002 - journals.lww.com
Study Design. The literature concerning the potential use of olfactory ensheathing cells for
repairing damaged spinal cord was reviewed. Objective. To engender a better …

Olfactory ensheathing cells promote locomotor recovery after delayed transplantation into transected spinal cord

J Lu, F Féron, A Mackay‐Sim, PME Waite - Brain, 2002 - academic.oup.com
We demonstrated recently that transplantation of olfactory ensheathing cells from the nasal
olfactory mucosa can promote axonal regeneration after complete transection of the spinal …

Reliable cell purification and determination of cell purity: crucial aspects of olfactory ensheathing cell transplantation for spinal cord repair

R Reshamwala, M Shah, L Belt… - Neural regeneration …, 2020 - journals.lww.com
Transplantation of olfactory ensheathing cells, the glia of the primary olfactory nervous
system, has been trialed for spinal cord injury repair with promising but variable outcomes in …

Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats

J Lu, F Féron, SM Ho, A Mackay-Sim, PME Waite - Brain research, 2001 - Elsevier
Recent reports have highlighted the potential therapeutic role of olfactory ensheathing cells
for repair of spinal cord injuries. Previously ensheathing cells collected from the olfactory …

Transplantation of olfactory mucosa following spinal cord injury promotes recovery in rats

K Iwatsuki, T Yoshimine, H Kishima, M Aoki… - …, 2008 - journals.lww.com
Several recent studies have demonstrated the potential therapeutic role of olfactory
ensheathing cells in spinal cord injury. The aim of this study was to elucidate whether grafts …

Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats

SC Barnett, JS Riddell - Journal of anatomy, 2004 - Wiley Online Library
One of the main research strategies to improve treatment for spinal cord injury involves the
use of cell transplantation. This review looks at the advantages and possible caveats of …

Crucial roles for olfactory ensheathing cells and olfactory mucosal cells in the repair of damaged neural tracts

JAK Ekberg, JA St John - The Anatomical Record, 2014 - Wiley Online Library
Olfactory ensheathing cells, the glial cells of the olfactory nervous system, exhibit unique
growth‐promoting and migratory properties that make them interesting candidates for cell …