[PDF][PDF] Neurobiologische und behaviorale Merkmale des Alterns im Rattenmodell

D Schulz - 2005 - docserv.uni-duesseldorf.de
Zusammenfassung Sowohl Rodentien als auch Menschen weisen im Alter interindividuelle
Differenzen auf, die im Vergleich zu jüngeren Populationen stark ausgeprägt sind und sich …

Individual differences in aging: behavioral and neural analyses.

DS Olton, A Markowska, SJ Breckler… - Biomedical and …, 1991 - europepmc.org
Aged populations have remarkable variability in recent memory and cognitive mapping.
Although some individuals may have substantial age-related impairments, others perform …

Use of rodents as models for the study of “normal aging”: conceptual and practical issues

EJ Masoro - Neurobiology of aging, 1991 - Elsevier
Certain guidelines may exist for selecting and using rodent models for aging research.
These are based, however, on only operational criteria because we presently lack good …

Assessment of age-associated cognitive deficits in rats: a tricky business

FJ van der Staay - Neuroscience & Biobehavioral Reviews, 2002 - Elsevier
Every living organism is affected by changes as a consequence of aging. Perhaps the most
appropriate concept to describe age-related changes is that of 'functional age'. Laboratory …

Individual differences in aging: behavioral and neurobiological correlates

AL Markowska, WS Stone, DK Ingram, J Reynolds… - Neurobiology of …, 1989 - Elsevier
The goal of this experiment was to determine the correlations among different behavioral
and neurobiological measures in aged rats. Aged Sprague-Dawley rats were given a battery …

Experimentelle Ansätze in der präklinischen Demenzforschung: Verhaltensforschung mit alten Ratten

J Traber, T Schuurman - Biologische Psychiatrie: Synopsis 1986/87, 1988 - Springer
Demente Patienten leiden unter eine Reihe funktioneller Störungen des zentralen
Nervensystems. So wird die Verminderung der kognitiven Leistungsfähigkeit (Lernen …

Comparison of different cognitive rat models of human aging

C LaSarge, M Nicolle - Animal models of human cognitive aging, 2009 - Springer
Multiple rat strains have been used for behavioral tests of cognitive function. This chapter
will discuss the advantages and disadvantages of commonly used rat strains in aging …

Age-related differences in behavior across the life span of the C57BL/6J mouse

RL Dean, J Scozzafava, JA Goas, B Regan… - Experimental aging …, 1981 - Taylor & Francis
Abstract C57BL/6J mice, representing four divergent age groups (ranging from 3 months to
31 months) were each tested on a number of behavioral procedures, selected to sample a …

[引用][C] Brain-behavior linkages in aged rodent models: strategies for examining individual differences

DK Ingram - Neurobiology of Aging, 1996 - Elsevier
BAXTER and Gallagher (1) have provided a brief review of approaches that can be takert to
link individual differences in the behavioral performance of aged rodents to possible …

Rodent models of brain aging and neurodegeneration

MJ Forster - Age, 2006 - Springer
Laboratory rats and mice have long been considered to be convenient models for the study
of aging in various mammalian systems. With regard to functions of the central nervous …