There is an increasing number of patients with diabetes mellitus in many countries. Diabetic
kidney disease, one of its microvascular complications, is also increasing markedly and has …

Introduction: Diabetes mellitus is increasingly common worldwide and is expected to affect
592 million people by 2035. The kidney is often involved. A key goal in treating diabetes is to …

Diabetic nephropathy is rapidly becoming the major cause of end-stage renal disease and
cardiovascular mortality worldwide. Standard of care therapies include strict glycemic control …

Type 2 Diabetes (T2D) is an important cause of renal dysfunction and the most common
cause of end-stage renal disease (ESRD). Diabetic nephropathy is also associated with an …

Chronic diabetes mellitus is associated with various complications such as retinopathy,
neuropathy, nephropathy, cardiomyopathy, vasculopathy, dermatopathy and …

Diabetic nephropathy is currently the most common cause of end stage renal disease not
only in the Western hemisphere but also in the developing nations. While the available …

Highlights•The pathogenesis of diabetic nephropathy is described.•Available anti-DN agents
with different status are summarized.•The multi-link-targeted agents are potential treatments …

Background: Diabetic nephropathy (DN) is currently the most common cause of end-stage
renal disease (ESRD). Although nowadays much is known about its classification …

Diabetes is currently one of the leading causes of end-stage renal failure requiring renal
replacement therapy in the Western World. About 15% to 20% of type 1 diabetic patients and …

Diabetic kidney disease remains the most common cause of end-stage kidney disease in
the world. Despite reductions in incidence rates of myocardial infarction and stroke in people …