Drug addiction is a brain disorder caused by the repetitive use of various chemicals which
alter normal functioning of the central nervous system with consequent behavioral …

Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to
addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals …

There is general consensus among preclinical researchers that dopamine plays an
important role in the development and persistence of addiction. However, the precise role of …

All drugs of abuse have been shown to act either directly or indirectly by increasing
dopamine neurotransmission within the limbic system. Thus, alcohol has been shown to …

Dopamine (DA) transmission is deeply affected by drugs of abuse, and alterations in DA
function are involved in the various phases of drug addiction and potentially exploitable …

Drug addiction includes complex neurobiological and behavioural processes. Acute
reinforcing effects of drugs of abuse are responsible for the initiation of drug addiction …

For several decades, addiction has come to be viewed as a disorder of the dopamine
neurotransmitter system; however, this view has not led to new treatments. In this Opinion …

Withdrawal from drugs of abuse is associated with major neurological and vegetative signs
of abstinence and with subjective aversive symptoms, such as anxiety, dysphoria …

Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …

Dopamine is monoamine neurotransmitter. Dopamine is produced in the dopaminergic
neurons in the ventral tegmental area of the substantia nigra, midbrain and the arcuate …