Heparin-induced thrombocytopenia (HIT) is a life-and limb-threatening prothrombotic,
immune-mediated adverse drug effect that occurs with unfractionated heparin and to a …

Purpose To review the perioperative management of antithrombotic therapy in cardiac
surgery, including the management of cardiopulmonary bypass (CPB) and off-pump surgery …

The peculiar pathogenesis of heparin-induced thrombocytopenia (HIT), involving a “self”
antigen—platelet factor 4 (PF4) bound to heparin—and resulting antibody-mediated platelet …

BACKGROUND: In contrast to other extracorporeal treatments no established regime exists
for anticoagulation with low‐molecular‐weight heparin (LMWH) in plasmapheresis therapy …

Diagnosis and management of heparin-induced thrombocytopenia. - Abstract - Europe
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(56) References Cited Methods for detecting the presence of antibodies to PF4/US PATENT
DOCUMENTS heparin/TSP-1 complexes in a biological Sample and for diagnosing Type 2 …

A substantial proportion of patients who undergo cardiac catheterization develop antibodies
directed against the heparin/platelet factor 4 (PF4) complex after the procedure, which have …

Discussion Bleeding in association with the administration of a low-molecular-weight
heparin in total joint replacement has been reported to occur in various anatomical sites …

Résumé Les thrombopénies induites par l'héparine résultent du développement d'anticorps
IgG spécifiques du facteur 4 plaquettaire. Plus fréquentes avec les héparines non …

Heparin use, both prophylactically and therapeutically, is prevalent among hospitalized
patients. Patients on heparin may develop a thrombocytopenia that is self-limited. Fewer …