Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer

I Astsaturov, RB Cohen, P Harari - Expert review of anticancer …, 2006 - Taylor & Francis
In this review, key aspects of epidermal growth factor receptor (EGFR) biology and the fruitful
translation of these fundamental findings into recent treatment advances in head and neck …

Long-term results of conventional radiotherapy versus accelerated hyperfractionated radiotherapy versus concomitant radiotherapy and chemotherapy in …

C Fallai, A Bolner, M Signor, A Gava… - Tumori …, 2006 - journals.sagepub.com
Aims and Background To compare conventional fractionation (CF) radiation therapy (RT),
arm A, versus a split-course accelerated hyperfractionated schedule (S-AHF), arm B, versus …

Dysphagia severity following chemoradiation and postoperative radiation for head and neck cancer

NP Nguyen, CC Moltz, C Frank, U Karlsson… - European journal of …, 2006 - Elsevier
OBJECTIVE: The purpose of the study is to evaluate dysphagia severity following
chemoradiation and postoperative radiation for head and neck cancer, and particularly the …

Growth factor-sensitive molecular targets identified in primary and metastatic head and neck squamous cell carcinoma using microarray analysis

H Miyazaki, V Patel, H Wang, JF Ensley, JS Gutkind… - Oral oncology, 2006 - Elsevier
Polypeptide growth factors play key roles in the processes of cell migration and invasion. In
this study, we have used cDNA microarrays to identify target genes whose expression is …

Recent new approaches to the treatment of head and neck cancer

MAR St John, E Abemayor, DTW Wong - Anti-cancer drugs, 2006 - journals.lww.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer in the
world and affects 50 000 Americans annually. During the past 20 years, treatments for …

Value of computed tomography‐based tumor volume as a predictor of outcomes in hypopharyngeal cancer after treatment with definitive radiotherapy

SW Chen, SN Yang, JA Liang, MH Tsai… - The …, 2006 - Wiley Online Library
Objectives: To investigate the value of pretreatment computed tomography (CT) volumetric
analysis for the prediction of treatment outcome in patients with hypopharyngeal cancer …

Does induction chemotherapy still have a role in larynx preservation strategies? The experience of Institut Catala d'Oncologia in stage III larynx carcinoma

M Majem, R Mesia, M Mañós, J Gomez… - The …, 2006 - Wiley Online Library
Background: Radiotherapy with concurrent cisplatin is the standard alternative to total
laryngectomy for patients with locally advanced laryngeal cancer. The value of induction …

Radiotherapeutic management of locally advanced head and neck cancer

SG Laskar, JP Agarwal, C Srinivas… - Expert review of …, 2006 - Taylor & Francis
Head and neck cancer management has undergone several paradigm shifts for several
relevant reasons. From the dismal experience with the use of radiotherapy as the sole …

Cetuximab and radiotherapy for head and neck cancer

MR Posner, LJ Wirth - New England Journal of Medicine, 2006 - Mass Medical Soc
The treatment of head and neck cancer is complex and difficult, both technically and
physically. Tumors in each site in the head and neck (oropharynx, hypopharynx, larynx, and …

Concomitant low‐dose cisplatin and three‐dimensional conformal radiotherapy for locally advanced squamous cell carcinoma of the head and neck: analysis of …

H Lau, S Brar, D Hao, J MacKinnon… - Head & Neck: Journal …, 2006 - Wiley Online Library
Background. Our center sought to implement a simple chemoradiotherapy schedule for
patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) …