[HTML][HTML] Clinical relevance of melanoma micrometastases (< 0.1 mm) in sentinel nodes: are these nodes to be considered negative?

ACJ van Akkooi, JHW de Wilt, C Verhoef, PIM Schmitz… - Annals of oncology, 2006 - Elsevier
As only about 20% of sentinel node (SN) positive melanoma patients have additional non-
SN lymph node involvement in the Completion Lymph Node Dissection (CLND) specimen …

Factors predictive of tumor-positive nonsentinel lymph nodes after tumor-positive sentinel lymph node dissection for melanoma

JH Lee, R Essner, H Torisu-Itakura, L Wanek… - Journal of clinical …, 2004 - ascopubs.org
Purpose Approximately 20% of sentinel node (SN) positive melanoma patients have
additional non-SN (NSN) metastasis. The rationale for this study was to identify the factors …

The microanatomic location of metastatic melanoma in sentinel lymph nodes predicts nonsentinel lymph node involvement

DJ Dewar, B Newell, MA Green, AP Topping… - Journal of Clinical …, 2004 - ascopubs.org
Purpose Sentinel node biopsy is now widely accepted as the most accurate prognostic
indicator in melanoma, and is important in guiding management of patients with clinical …

Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 …

ACJ van Akkooi, ZI Nowecki, C Voit… - Annals of …, 2008 - journals.lww.com
Summary Background Data: The more intensive sentinel node (SN) pathologic workup, the
higher the SN-positivity rate. This is characterized by an increased detection of cases with …

Microscopic tumor burden in sentinel lymph nodes predicts synchronous nonsentinel lymph node involvement in patients with melanoma

JE Gershenwald, RHI Andtbacka, VG Prieto… - Journal of clinical …, 2008 - ascopubs.org
Purpose We and others have demonstrated that additional positive lymph nodes (LNs) are
identified in only 8% to 33% of patients with melanoma who have positive sentinel LNs …

Characterization of micrometastatic disease in melanoma sentinel lymph nodes by enhanced pathology: recommendations for standardizing pathologic analysis

K Spanknebel, DG Coit, SC Bieligk… - The American journal …, 2005 - journals.lww.com
Lymphatic mapping and sentinel lymph node (SLN) biopsy are widely used as a staging
technique for patients with cutaneous malignant melanoma who are at risk for metastases …

Pathologic review of negative sentinel lymph nodes in melanoma patients with regional recurrence: a clinicopathologic study of 1152 patients undergoing sentinel …

LXL Li, RA Scolyer, SK Vivian… - The American journal …, 2003 - journals.lww.com
A sentinel lymph node (SLN) that is melanoma negative by pathologic examination implies
absence of melanoma metastasis to that regional lymph node field. However, a small …

Sentinel lymph nodes in malignant melanoma: extended histopathologic evaluation improves diagnostic precision

HN Abrahamsen, SJ Hamilton‐Dutoit… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND The optimal technique for sentinel lymph node (SN) assessment in patients
with melanoma is controversial. Molecular analysis (reverse transcriptase–polymerase …

Factors predictive of nonsentinel lymph node involvement and clinical outcome in melanoma patients with metastatic sentinel lymph node

CR Rossi, GL De Salvo, E Bonandini… - Annals of Surgical …, 2008 - Springer
Background Identification of melanoma patients who need completion lymphadenectomy
and adjuvant treatment after positive sentinel lymph node (SLN) biopsy would be a …

[HTML][HTML] The prognostic significance of sentinel node tumour burden in melanoma patients: an international, multicenter study of 1539 sentinel node-positive …

APT van der Ploeg, ACJ van Akkooi, LE Haydu… - European journal of …, 2014 - Elsevier
Introduction Sentinel node (SN) biopsy (SNB) and completion lymph node dissection
(CLND) when SN-positive have become standard of care in most cancer centres for …