In this issue of the Journal of Applied Physiology, Kairaitis et al.(9) examine the control of
pharyngeal extraluminal tissue pressure by mandibular advancement and jaw position …

OBSTRUCTIVE SLEEP APNEA IS characterized by repetitive episodes of upper airway
obstruction during sleep, leading to oxyhemoglobin desaturation, recurrent arousals, and …

Lateral pharyngeal fat pad compression of the upper airway (UA) wall is thought to influence
UA size in patients with obstructive sleep apnea. We examined interactions between acute …

Transmural pressure at any level in the upper airway is dependent on the difference
between intraluminal airway and extraluminal tissue pressure (ETP). We hypothesized that …

The pharyngeal airway is surrounded by soft tissues that are also enclosed by bony
structures such as the mandible, maxilla, and cervical spine. The passive pharyngeal airway …

Abstract Study Objectives: To investigate the mechanisms via which lung volume related
caudal tracheal traction decreases upper airway collapsibility. Design: Acute physiological …

We studied the impact of wall strain and surrounding pressure on the onset of airflow
limitation in a thin-walled “floppy” tube model. A vacuum source-generated steady-state …

In collapsible biologic conduits, occlusion and cessation of flow occur when upstream
pressure falls below a critical pressure (Pcrit). To examine the relationship between Pcrit …

We examined the influence of pharyngeal dilator muscle activity on upper airway
extraluminal tissue pressure (ETP) distribution and upper airway patency. We studied seven …

Lung volume dependence of pharyngeal airway patency suggests involvement of lung
volume in pathogenesis of obstructive sleep apnea. We examined the structural interaction …