Caffeine is the most widely consumed psychoactive drug, with the prevalence of use
approaching 80% of the world's population. In stark contrast to most stimulants, caffeine is …

Caffeine is the most widely consumed psychoactive substance in the world. However, there
is controversy about whether becoming addicted to caffeine is possible and a lack of well …

Caffeine is widely consumed for its psychoactive effects worldwide. No pre-clinical study has
established reliable caffeine self-administration, but we found that caffeine can enhance the …

Previously, we demonstrated that caffeine dose-dependently reinstated extinguished
cocaine-taking behavior in rats. In the present study, we determined whether this effect of …

Rationale Caffeine is one of the psychoactive substances most widely used as an adulterant
in illicit drugs, such as cocaine. Animal studies have demonstrated that caffeine is able to …

The prevalence of tobacco smoking and coffee drinking place nicotine and caffeine among
the most used licit drugs in many societies and their consumption is often characterised by …

Background: Caffeine consumption by children and adolescents has risen dramatically in
recent years, yet the lasting effects of caffeine consumption during adolescence remain …

Rationale Caffeine and nicotine are the most commonly co-used psychostimulants.
However, it is still unclear whether caffeine exposure enhances nicotine-seeking behavior …

Interactions between caffeine and cocaine have been demonstrated in a number of
behavioral paradigms. The present study was undertaken in an attempt to determine …

Several recent studies have shown that caffeine potentiates the reinforcing, discriminative
stimulus, and motor activating effects of cocaine in rats. The present study was designed to …