OBJECTIVE: To find if a particular quality score was better than others at validly scoring the
quality of randomized controlled trials, both by examining the consistency of dividing studies …

ContextAlthough it is widely recommended that clinical trials undergo some type of quality
review, the number and variety of quality assessment scales that exist make it unclear how …

OBJECTIVE: Many reviews specifically aimed to assess the quality of randomized controlled
trials (RCTs). We evaluated the quality of reporting in such reviews. STUDY DESIGN AND …

The best evidence on the efficacy of medical interventions is provided by high-quality trials
summarized in high-quality systematic reviews or meta-analyses. The methodological …

Meta-analysis is a method of synthesizing evidence from multiple sources. It has been
increasingly applied to combine results from randomized trials of therapeutic strategies …

This chapter contains section titled: Summary Points A Framework for Methodological
Quality Dimensions of Internal Validity Empirical Evidence of Bias Dimensions of External …

Meta-analytic investigations sometimes use assessements of research qualityaccording to a
formal protocol as a tool for improving research synthesis. We asked whether a particular …

The quality assessment of non-randomized studies is an important component of a thorough
meta-analysis of nonrandomized studies. Low quality studies can lead to a distortion of the …

BACKGROUND AND OBJECTIVE: To review current practice in the assessment of the
quality of original observational studies included in systematic reviews. MATERIALS AND …

Article-at-a-Glance Background Evidence-based medicine, clinical practice guidelines,
quality and value of health services, and science-based decision making are becoming …