Tonic activation of the sympathetic nervous system is a major factor contributing to
hypertension in patients with chronic renal failure. Besides its role in blood pressure …

Objective To review the current literature on sympathetic mediation of hypertension in
chronic renal failure. Background Hypertension is present in the vast majority of patients with …

Much evidence indicates increased sympathetic nervous activity (SNA) in renal disease.
Renal ischemia is probably a primary event leading to increased SNA. Increased SNA often …

The potential involvement of sympathetic overactivity has been neglected in this population
despite accumulating experimental and clinical evidence suggesting a crucial role of …

Hypertension is present in the majority of patients with chronic renal failure and constitutes a
major risk factor for the very high cardiovascular morbidity and mortality in this patient …

There is a dramatic increase in patients with end-stage re-nal failure due to diabetic
nephropathy, chronic glomerulonephritis and uncontrolled hypertension all over the world …

Sympathetic hyperactivity plays an important and distinct role in hypertension associated
with chronic renal failure (CRF). Renal ischemia, elevated angiotensin II, and suppressed …

Previous research in end stage renal failure has focused on the renin-angiotensin-system.
Today, we know, that in chronic renal failure sympathetic overactivity plays a pivotal role for …

Sympathetic activation is of crucial importance for both the blood pressure increase and the
high morbidity and mortality in end-stage renal disease. 1 The mechanisms responsible for …

Cardiovascular morbidity and mortality is exceedingly high in patients with chronic renal
failure. Sympathetic overactivity is an important pathomechanism contributing to progression …