The activating mutation FGFR3-R248C in the D2–D3 linker region of fibroblast growth factor
receptor 3 leads as germline mutation to the neonatal lethal syndrome thanatophoric …

A truncated form of the type 1 fibroblast growth factor receptor (FGFR1) lacking most of its
cytoplasmic domain was tested for its ability to inhibit signal transduction by each of three …

Fibroblast growth factor (FGF) receptor (FGFR) gene family consists of at least four receptor
tyrosine kinases that transduce signals important in a variety of developmental and …

Alternatively spliced variants of fibroblast growth factor receptor 1 mRNA are predicted to
encode secreted forms and membrane-bound forms of receptors. The predicted amino acid …

Recurrent missense fibroblast growth factor receptor 3 (FGFR3) mutations have been
ascribed to skeletal dysplasias of variable severity including the lethal neonatal …

Fibroblast growth factors (FGF) regulate the growth and differentiation of cells through
complex combinatorial signaling pathways. There are nine ligands that interact with a family …

A novel, low molecular weight, intracellular isoform of FGF receptor‐1 (FGFR‐1) was
identified in embryonic chicken tissues using several antibodies specific for different …

The fibroblast growth factor receptor 1 (flg) contains eight acidic amino acids between the
first and second immunoglobulin domain. This report examines the role of the acidic domain …

To assess the effect (s) of the C-terminal domain on FGFR2 function, we engineered a series
of mutant FGFR2 cDNAs encoding deletions in the C-terminus of the receptor and compared …

We have studied the expression of two of the receptors for fibroblast growth factors, FGFR‐1
and FGFR‐2, in response to ligand binding and in embryonal carcinoma (EC cells)> …