[HTML][HTML] Aged garlic extract has chemopreventative effects on 1, 2-dimethylhydrazine-induced colon tumors in rats

T Katsuki, K Hirata, H Ishikawa, N Matsuura, S Sumi… - The Journal of …, 2006 - Elsevier
Garlic has been reported to have chemopreventive effects against a variety of cancers.
However, different garlic preparations contain different constituents. We investigated the …

[HTML][HTML] Aged garlic extract inhibits 1, 2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation

H Jikihara, G Qi, K Nozoe, M Hirokawa… - Oncology …, 2015 - spandidos-publications.com
Garlic and its constituents are reported to have a preventive effect against colorectal cancer
in animal models. Aged garlic extract (AGE), which is produced by natural extraction from …

[HTML][HTML] Aged garlic extract inhibits angiogenesis and proliferation of colorectal carcinoma cells

N Matsuura, Y Miyamae, K Yamane, Y Nagao… - The Journal of …, 2006 - Elsevier
Because colorectal cancer is likely to develop in many people at some point during their
lives, prevention has become a high priority. Diet and nutrition play an important role during …

[HTML][HTML] Aged garlic extract has potential suppressive effect on colorectal adenomas in humans

S Tanaka, K Haruma, M Yoshihara, G Kajiyama… - The Journal of …, 2006 - Elsevier
Epidemiological and animal studies suggest AGE and its organosulfur constituents, such as
S-allylcysteine and S-allylmercaptocysteine have anticarcinogenic effects. To confirm these …

Optimal dose of garlic to inhibit dimethylhydrazine‐induced colon cancer

JY Cheng, CL Meng, CC Tzeng… - World journal of surgery, 1995 - Wiley Online Library
This study was designed to investigate the optimal dose of garlic during long‐term feeding
and its preventive and therapeutic effects on colon cancer in rats induced by 1, 2 …

[PDF][PDF] Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study

S Tanaka, K Haruma, M Kunihiro, S Nagata… - Hiroshima J Med …, 2004 - core.ac.uk
Aged garlic extract (AGE) is a material that has the possibility of a cancer-preventive effect
according to epidemiologic and animal studies. In order to confirm the effects of AGE on …

New pharmacological activities of garlic and its constituents

H Sumiyoshi - Nihon yakurigaku zasshi. Folia pharmacologica …, 1997 - europepmc.org
According to the recent pharmacological findings, garlic is a preventive rather than
therapeutic. Epidemiological studies in China, Italy and USA showed the inverse …

[HTML][HTML] Aged garlic extract inhibits development of putative preneoplastic lesions in rat hepatocarcinogenesis

N Uda, N Kashimoto, I Sumioka, E Kyo, S Sumi… - The Journal of …, 2006 - Elsevier
ABSTRACT A unique garlic preparation, aged garlic extract (AGE), was examined for its
modifying effect on diethylnitrosamine (DEN)-induced neoplasia of the liver in male F344 …

[HTML][HTML] Alleviation by Garlic of Antitumor Drug–Induced Damage to the Intestine

T Horie, S Awazu, Y Itakura, T Fuwa - The Journal of nutrition, 2001 - Elsevier
Antitumour drugs such as methotrexate (MTX) and 5-fluorouracil (5-FU) induce intestinal
damage. This is a serious side effect of cancer chemotherapy. The present studies …

[PDF][PDF] Inhibition of 1, 2-dimethylhydrazine-induced mucin-depleted foci and O6-methylguanine DNA adducts in the rat colorectum by boiled garlic powder

T Chihara, K Shimpo, T Kaneko, H Beppu… - Asian Pac J Cancer …, 2010 - researchgate.net
The scavenging capacity of reactive oxygen species, such as hydroxyl radicals, is reported
not to decrease in boiled garlic (an odorless garlic preparation). We therefore examined the …