Two of the four human FGF8 splice isoforms, FGF8a and FGF8b, are expressed in the mid-
hindbrain region during development. Although the only difference between these isoforms …

Early patterning of the vertebrate midbrain and cerebellum is regulated by a mid/hindbrain
organizer that produces three fibroblast growth factors (FGF8, FGF17 and FGF18). The …

Fibroblast growth factors are essential molecules for development. Here we characterize
Fgf17, a new member of the fibroblast growth factor (FGF) family. The Fgf17 gene maps to …

Members of the fibroblast growth factor (Fgf) family are important signaling molecules in
several inductive and patterning processes, and act as brain organizer-derived signals …

The Fgf8 gene is expressed in developing limb and craniofacial structures, regions known to
be important for growth and patterning of the mouse embryo. Although Fgf8 is alternatively …

The vertebrate Fgf8 gene produces multiple protein isoforms by alternative splicing. Two
evolutionarily conserved spliceforms, Fgf8a and Fgf8b, exhibit distinct bioactivities, with …

We used Fgf10-lacZ reporter mice to investigate the distribution and fate of Fgf10-expressing
cells in the developing and adult mouse brain. We find that the domain of Fgf10 expression …

The actions of fibroblast growth factors (FGFs) are mediated via a family of four closely
related FGF receptor genes (FGFRs 1-4). FGFR1, FGFR2, and FGFR4 have unique patterns …

Complex spatiotemporal expression patterns of fgf3 and fgf8 within the developing zebrafish
forebrain suggest their involvement in its regionalisation and early development. These …

FGF8 is known to be an important regulator of forebrain development. Here, we investigated
the effects of varying the level of Fgf8 expression in the mouse forebrain. We detected two …