The narrowing or occlusion of the upper airway (UA) during sleep has been attributed to
several factors. An abnormal anatomy of the UA, pathological and insufficient reflex …

The most accepted theory regarding the pathogenesis of obstructive sleep apnea (OSA)
centers on an anatomical deficiency in the upper airway. During sleep, the loss of …

The pathogenesis of obstructive sleep apnea (OSA) has been under investigation for over
25 years, during which a number of factors that contribute to upper airway (UA) collapse …

Sleep apnea syndrome (SAS) results from modification in the control of respiration and of
upper airway caliber during sleep. Although there is some overlap between central (CSAS) …

Repeated obstruction and closure of the upper airway, sporadic hypoxic episodes, and
sympathetic activity are symptoms of obstructive sleep apnea (OSA). Obstructive sleep …

The obstructive sleep apnoea syndrome (OSAS) is characterised by repetitive upper airway
obstructions leading to snoring, hypopnoeas and apnoeas. Sleep fragmentation and arterial …

In patients with obstructive sleep apnea (OSA), there is evidence of histologic changes to
upper airway tissues, which may explain abnormalities in sensorimotor and reflex activity in …

The pathophysiology of obstructive sleep apnoea syndrome (OSAS) is complex and
incompletely understood, but is principally based on an imbalance between the collapsing …

The onset of sleep is associated with a reduction in upper airway patency and an increase in
resistance, an effect observed in normal humans and animals, and typically present in …

Over the last decade, considerable work has focused on various anatomic and physiologic
factors in the search for etiology and pathophysiology of obstructive sleep apnea (OSA) …