We describe extracellular interactions between fibronectin (Fn) and vascular endothelial
growth factor (VEGF) that influence integrin-growth factor receptor crosstalk and cellular …

Interactions between integrins and growth factor receptors play a critical role in the
development and healing of the vasculature. This study mapped two binding domains on …

Vascular endothelial growth factor (VEGF), a major factor mediating endothelial cell survival,
migration, and proliferation during angiogenesis, is expressed as five splice variants (121 …

Regulation of angiogenesis involves interactions between vascular endothelial growth factor
(VEGF) and components of the extracellular matrix, including fibronectin and heparan …

Vascular endothelial growth factor receptor-1 (VEGFR-1) is a tyrosine kinase receptor for
several growth factors of the VEGF family. Endothelial cells express a membrane-spanning …

Background: Vascular endothelial growth factor (VEGF) is an endothelial cell-specific
mitogen and is a potent angiogenic and vascular permeabilizing factor. VEGF is also an …

Vascular endothelial growth factor (VEGF) is a strong angiogenic mitogen and plays
important roles in angiogenesis under various pathophysiological conditions. The in vivo …

Angiogenesis is a highly regulated process orchestrated by the VEGF system.
Heparin/heparan sulfate proteoglycans and neuropilin-1 (NRP-1) have been identified as co …

Hypoxia is one of the major signals that induces angiogenesis. Hypoxic conditions lead to
reduced extracellular pH. Vascular endothelial growth factor (VEGF) binding to endothelial …

Substrate-bound FGF2 promotes endothelial cell adhesion by interacting with α v β 3
integrin. Here, endothelial GM7373 cells spread and organize focal adhesion plaques on …