Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which
replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function …

Background The genomes of the three parasitic protozoa Trypanosoma cruzi, Trypanosoma
brucei and Leishmania major are the main subject of this study. These parasites are …

Several biological processes in Trypanosoma brucei are affected by chromatin structure,
including gene expression, cell cycle regulation, and life-cycle stage differentiation. In …

The pentatricopeptide repeat (PPR), a degenerate 35-amino-acid motif, defines a novel
eukaryotic protein family. Plants have 400 to 500 distinct PPR proteins, whereas other …

Centrin is a calcium-binding centrosome/basal body–associated protein involved in
duplication and segregation of these organelles in eukaryotes. We had shown that …

Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes
are unusual organisms in many aspects of its genetics and molecular and cellular biology …

ATP‐binding cassette (ABC) transporters represent an important family of membrane
proteins involved in drug resistance and other biological activities. The present work reports …

Flagellates of the Leishmania donovani complex are causative agents of human cutaneous
and visceral leishmaniasis. The complex is comprised of L. donovani, Leishmania infantum …

Mitogen-activated protein kinases are well-known mediators of signal transduction of higher
eukaryotes regulating important processes like proliferation, differentiation, stress response …

Surface proteins of mucosal microbial pathogens play multiple and essential roles in
initiating and sustaining the colonization of the heavily defended mucosa. The protist …