The neuronal Ca2+-binding protein 2 (NECAB2) interacts with the adenosine A2A receptor and modulates the cell surface expression and function of the receptor
L Canela, R Luján, C Lluís, J Burgueño, J Mallol… - Molecular and Cellular …, 2007 - Elsevier
Heptaspanning membrane also known as G protein-coupled receptors (GPCR) do interact
with a variety of intracellular proteins whose function is regulate receptor traffic and/or …
with a variety of intracellular proteins whose function is regulate receptor traffic and/or …
NCS-1 associates with adenosine A2A receptors and modulates receptor function
Modulation of G protein-coupled receptor (GPCR) signaling by local changes in intracellular
calcium concentration is an established function of Calmodulin (CaM) which is known to …
calcium concentration is an established function of Calmodulin (CaM) which is known to …
Are A3 adenosine receptors expressed in the brain?
SA Rivkees, S Thevananther, H Hao - Neuroreport, 2000 - journals.lww.com
An increasing number of reports suggest a role for A3 adenosine receptors (A3ARs) in
mediating adenosine action in the central nervous system. However, studies of A3AR …
mediating adenosine action in the central nervous system. However, studies of A3AR …
Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector
TE Scammell, E Arrigoni, MA Thompson… - Journal of …, 2003 - Soc Neuroscience
Adenosine is a ubiquitous neuromodulator that increases sleep, inhibits seizures, and
promotes neuroprotection. Many of these effects are mediated by A1 receptors, but A1 …
promotes neuroprotection. Many of these effects are mediated by A1 receptors, but A1 …
Partners for adenosine A1 receptors
G protein-coupled receptors (GPCRs) are targets for therapy in a variety of neurological
diseases. Using adenosine A 1 receptors (A 1 Rs) as paradigm of GPCRs, this review …
diseases. Using adenosine A 1 receptors (A 1 Rs) as paradigm of GPCRs, this review …
A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase
E Gracia, K Perez-Capote, E Moreno… - Biochemical …, 2011 - portlandpress.com
A2ARs (adenosine A2A receptors) are highly enriched in the striatum, which is the main
motor control CNS (central nervous system) area. BRET (bioluminescence resonance …
motor control CNS (central nervous system) area. BRET (bioluminescence resonance …
Ecto-5′-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions
Adenosine is a neuromodulator acting through inhibitory A1 receptors (A1Rs) and facilitatory
A2ARs, which have similar affinities for adenosine. It has been shown that the activity of …
A2ARs, which have similar affinities for adenosine. It has been shown that the activity of …
Adenosine A2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons
FM Mouro, DM Rombo, RB Dias… - British Journal of …, 2018 - Wiley Online Library
Background and Purpose NMDA receptors play a key role in both synaptic plasticity and
neurodegeneration. Adenosine is an endogenous neuromodulator and through membrane …
neurodegeneration. Adenosine is an endogenous neuromodulator and through membrane …
Adenosine A3 receptors are located in neurons of the rat hippocampus
Adenosine is a neuromodulator acting mainly via inhibitory A 1 and facilitatory A 2A
receptors. Whole tissue PCR also identified adenosine A 3 receptors in the brain and A 3 …
receptors. Whole tissue PCR also identified adenosine A 3 receptors in the brain and A 3 …
[HTML][HTML] Specific ligands for the adenosine receptor family
KA Jacobson - RBI Neurotransmissions, 1996 - everest.bic.nus.edu.sg
The principal mechanism by which caffeine and other alkylxanthines act as physiological
stimulants is by blocking the effects of the ubiquitous neuromodulator adenosine [1, 2] …
stimulants is by blocking the effects of the ubiquitous neuromodulator adenosine [1, 2] …