Untitled Page 1 Page 2 CAT3: a new bioinformatics tool for prediction of Caspase -3
substrate cleavage site By Muneef Ayyash Department of Scientific Computing Birzeit …

Objetivo: Screening and validation of putative caspase substrates using CaSpredictor
software. Métodos e Resultados: We have chosen an arbitrary CASP score= 0.57, where the …

Motivation: In vitro studies have shown that the most remarkable catalytic features of
caspases, a family of cysteineproteases, are their stringent specificity to Asp (D) in the S1 …

Because of its wide range of substrates, caspase‐3, a main executioner among apoptosis‐
related caspases, is thought to have many unknown substrates that have remained …

Caspases belong to a unique class of cysteine proteases which function as critical effectors
of apoptosis, inflammation and other important cellular processes. Caspases cleave …

Motivation: Caspases and granzyme B (GrB) are important proteases involved in
fundamental cellular processes and play essential roles in programmed cell death, necrosis …

Caspases belong to a unique class of cysteine proteases which play critical roles in
important processes such as cell death, differentiation and inflammation. The central feature …

Motivation: The caspase family of cysteine proteases play essential roles in key biological
processes such as programmed cell death, differentiation, proliferation, necrosis and …

CHAPTER ONE Page 1 IDENTIFICATION OF CASPASE-2 SPECIFICITY AND
SUBSTRATES Submitted by Tanja Kitevska Bachelor of Biomedical Science (Biochemistry …

Background Caspases are a family of proteases that have central functions in programmed
cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate …